Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984624 | 0.93 | GRM5 (0.41) | GRM5SMN1; SMN2HTR7MAPTKMT2A | |
| SCHEMBL6981707 | 0.84 | SMN1; SMN2 (0.43) | GRM5SMN1; SMN2HTR7MAPTKMT2A | |
| SCHEMBL6978571 | 0.81 | KMT2A (0.44) | GRM5SMN1; SMN2HTR7MAPTKMT2A | |
| SCHEMBL6979020 | 0.77 | SMN1; SMN2 (0.49) | GRM5SMN1; SMN2KMT2AAKR1C3ALDH1A1 | |
| SCHEMBL6979028 | 0.77 | SMN1; SMN2 (0.49) | GRM5SMN1; SMN2KMT2AAKR1C3ALDH1A1 | |
| SCHEMBL6978386 | 0.77 | KMT2A (0.49) | GRM5SMN1; SMN2HTR7MAPTKMT2A | |
| SCHEMBL6978390 | 0.77 | KMT2A (0.49) | GRM5SMN1; SMN2HTR7MAPTKMT2A | |
| SCHEMBL6984615 | 0.76 | KMT2A (0.51) | SMN1; SMN2KMT2AAKR1C3ALDH1A1MEN1 | |
| SCHEMBL6981698 | 0.76 | CCR1 (0.47) | SMN1; SMN2KMT2ALMNAAKR1C3ALDH1A1 | |
| SCHEMBL8405526 | 0.75 | SMN1; SMN2 (0.42) | GRM5SMN1; SMN2HTR7KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771565-B1 | Angiogenesis inhibitor | SENJU PHARMA CO (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6214800-B1 | ANGIOGENESIS INHIBITORS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2001-04-10 | — | — | US | disclosed |
| US-6057290-A | ADMINISTERING A CYSTEINE PROTEASE INHIBITOR TO A PATIENT FOR INHIBITING ANGIOGENESIS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0928786-A1 | Angiogenesis inhibitor | Senju Pharmaceutical Co., Ltd. (JP) | 1999-07-14 | — | — | EP | disclosed |
| EP-0927716-A1 | Angiogenesis inhibitor | Senju Pharmaceutical Co., Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |
| EP-0838460-A1 | PIPERAZINE DERIVATIVES AND USE OF THE SAME | Senju Pharmaceutical Co., Ltd. (JP) | 1998-04-29 | — | — | EP | disclosed |
| EP-0771565-A2 | Angiogenesis inhibitor | Senju Pharmaceutical Co., Ltd. (JP) | 1997-05-07 | — | — | EP | disclosed |