Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 2/20 | 0.44 |
| ▸ | TGM6 | O95932 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982389 | 0.95 | TGM2 (0.47) | KMT2AALDH1A1MEN1KDM4EGAA | |
| SCHEMBL6981151 | 0.86 | TGM2 (0.45) | KMT2AALDH1A1MEN1TGM2TGM6 | |
| SCHEMBL6985309 | 0.86 | CAPN1 (0.54) | KMT2AALDH1A1MEN1KDM4EGAA | |
| SCHEMBL6979028 | 0.82 | SMN1; SMN2 (0.49) | KMT2AALDH1A1MEN1GAACCR1 | |
| SCHEMBL6979020 | 0.82 | SMN1; SMN2 (0.49) | KMT2AALDH1A1MEN1GAACCR1 | |
| SCHEMBL6978563 | 0.81 | CCR1 (0.50) | KMT2AALDH1A1CCR1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6981698 | 0.79 | CCR1 (0.47) | KMT2AALDH1A1CCR1SMN1; SMN2AKR1C3 | |
| SCHEMBL8405526 | 0.79 | SMN1; SMN2 (0.42) | KMT2AALDH1A1MEN1GAATGM2 | |
| SCHEMBL6981807 | 0.77 | SMN1; SMN2 (0.43) | KMT2AALDH1A1MEN1GAACCR1 | |
| SCHEMBL6981803 | 0.77 | ADAM10 (0.40) | KMT2AALDH1A1MEN1TGM2TGM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6551999-B1 | For therapy and prophylaxis of angiogenesis associated with wound healing, inflammation, growth of tumor and the like; angiogenesis as seen in diabetic retinopathy, prematurity retinopathy, retinal venous occlusion, metastasis of tumors | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-0771565-B1 | Angiogenesis inhibitor | SENJU PHARMA CO (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6214800-B1 | ANGIOGENESIS INHIBITORS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2001-04-10 | — | — | US | disclosed |
| US-6057290-A | ADMINISTERING A CYSTEINE PROTEASE INHIBITOR TO A PATIENT FOR INHIBITING ANGIOGENESIS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0928786-A1 | Angiogenesis inhibitor | Senju Pharmaceutical Co., Ltd. (JP) | 1999-07-14 | — | — | EP | disclosed |
| EP-0927716-A1 | Angiogenesis inhibitor | Senju Pharmaceutical Co., Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |
| EP-0838460-A1 | PIPERAZINE DERIVATIVES AND USE OF THE SAME | Senju Pharmaceutical Co., Ltd. (JP) | 1998-04-29 | — | — | EP | disclosed |
| EP-0771565-A2 | Angiogenesis inhibitor | Senju Pharmaceutical Co., Ltd. (JP) | 1997-05-07 | — | — | EP | disclosed |