SCHEMBL698258

SCHEMBL698258

O=C(O)NN1CCOCC1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52
CYP2D6 P10635 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.47
EPHX2 P34913 1/20 0.46
LIPE Q05469 1/20 0.43
HTT P42858 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ALDH1A1 P00352 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5112582 0.98 CA12 (0.50) CA12CA1CA2CA9CYP2D6
Morpholine SCHEMBL910450 0.88 CYP2D6 (0.44) CA12CA1CA2CA9CYP2D6
SCHEMBL4615811 0.81
SCHEMBL698257 0.80 CA12 (0.52) CA12CA1CA2CA9CYP2D6
SCHEMBL3422335 0.78 CA12 (0.50) CA12CA1CA2CA9CYP2D6
SCHEMBL2520895 0.78 CA12 (0.50) CA12CA1CA2CA9CYP2D6
SCHEMBL365772 0.78 EPHX2 (0.53) CA12CA1CA2CA9CYP2D6
SCHEMBL3870049 0.78 CA12 (0.50) CA12CA1CA2CA9CYP2D6
SCHEMBL3077421 0.78 CA12 (0.50) CA12CA1CA2CA9CYP2D6
SCHEMBL5199864 0.78 CA12 (0.50) CA12CA1CA2CA9CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116196427-A Compositions and methods for immune-mediated cancer therapy 泰克利森有限公司 2023-06-02 CN claimed
US-20230133566-A1 COMPOSITIONS AND METHODS FOR IMMUNE-MEDIATED CANCER THERAPY Teclison, Inc. 2023-05-04 US claimed
US-20190070186-A1 COMPOSITIONS AND METHODS FOR IMMUNE-MEDIATED CANCER THERAPY Teclison, Inc. 2019-03-07 US claimed
EP-2066497-B1 MANUFACTURING METHODS FOR METAL CLAD LAMINATES INKTEC CO LTD (KR) 2018-11-07 EP claimed
EP-2013298-B1 COMPOSITIONS FOR FORMING REFLECTING LAYER HAVING ORGANIC SILVER COMPLEXES,AND METHOD FOR PREPARING REFLECTING LAYER USING SAME INKTEC CO LTD (KR) 2018-06-27 EP claimed
EP-2052043-B1 PROCESS FOR PREPARATION OF SILVER NANOPARTICLES, AND THE COMPOSITIONS OF SILVER INK CONTAINING THE SAME INKTEC CO LTD (KR) 2016-10-12 EP claimed
EP-1846422-B1 ORGANIC SILVER COMPLEXES, THEIR PREPARATION METHODS AND THEIR METHODS FOR FORMING THIN LAYERS INKTEC CO LTD (KR) 2016-04-13 EP claimed
US-9090785-B2 Silver ink composition INKTEC CO., LTD. (KR) 2015-07-28 US claimed
EP-2752470-A1 Process for preparation of silver nanoparticles, and the compositions of silver ink containing the same Inktec Co., Ltd. (KR) 2014-07-09 EP claimed
US-20140065139-A1 Induction of Tumor Hypoxia for Cancer Therapy VIRGINIA COMMONWEALTH UNIVERSITY (US) 2014-03-06 US claimed
US-20120087913-A1 INDUCTION OF TUMOR HYPOXIA FOR CANCER THERAPY VIRGINIA COMMONWEALTH UNIVERSITY 2012-04-12 US claimed
US-20100189901-A1 PROCESS FOR PREPARATION OF SILVER NANOPARTICLES, AND THE COMPOSITIONS OF SILVER INK CONTAINING THE SAME INKTEC CO., LTD. (KR) 2010-07-29 US claimed
WO-2009126705-A2 INDUCTION OF TUMOR HYPOXIA FOR CANCER THERAPY VIRGINIA COMMONWEALTH UNIVERSITY (US) 2009-10-15 WO claimed
EP-2052043-A1 PROCESS FOR PREPARATION OF SILVER NANOPARTICLES, AND THE COMPOSITIONS OF SILVER INK CONTAINING THE SAME Inktec Co., Ltd. (KR) 2009-04-29 EP claimed
WO-2008018718-A1 PROCESS FOR PREPARATION OF SILVER NANOPARTICLES, AND THE COMPOSITIONS OF SILVER INK CONTAINING THE SAME INKTEC CO., LTD. (KR) 2008-02-14 WO claimed
EP-0637965-B1 ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES ISIS PHARMACEUTICALS INC (US) 2002-10-16 EP claimed
WO-1997038114-A1 PUROMYCIN-SENSITIVE AMINOPEPTIDASES NOVARTIS AG (CH) 1997-10-16 WO claimed
WO-1996005298-A1 ANTITUMOR ANTISENSE OLIGONUCLEOTIDES CIBA-GEIGY AG (CH) 1996-02-22 WO claimed
EP-0088377-B1 CARBAMATE AND CARBONATE SALTS OF TERTIARY AMINES AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-04-22 EP claimed
US-4542214-A DELAYED ACTION POLYURETHANE CATALYSTS AIR PRODUCTS AND CHEMICALS, INC. (US) 1985-09-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100189901-A1 PROCESS FOR PREPARATION OF SILVER NANOPARTICLES, AND THE COMPOSITIONS OF SILVER INK CONTAINING THE SAME NRAS, C1R, BAP1 CA12 725/4885CA1 260/4885CA2 156/4885
US-20230133566-A1 COMPOSITIONS AND METHODS FOR IMMUNE-MEDIATED CANCER THERAPY CD47, HIF1AN, HIF1A CA12 35/4885CA1 39/4885CA2 89/4885
US-20140065139-A1 Induction of Tumor Hypoxia for Cancer Therapy HIF1A, HIF1AN, HYOU1 CA12 91/4885CA1 28/4885CA2 20/4885
US-20120087913-A1 INDUCTION OF TUMOR HYPOXIA FOR CANCER THERAPY HIF1A, HIF1AN, HYOU1 CA12 91/4885CA1 28/4885CA2 20/4885
US-20190070186-A1 COMPOSITIONS AND METHODS FOR IMMUNE-MEDIATED CANCER THERAPY CD47, HIF1AN, HIF1A CA12 35/4885CA1 39/4885CA2 89/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.