Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 15/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3909631 | 0.90 | HPGD (0.60) | HPGDHTR1AKMT2ADRD2 | |
| SCHEMBL6981877 | 0.87 | HTR1A (0.62) | HTR1A | |
| SCHEMBL14525212 | 0.86 | HPGD (0.43) | HPGDHTR1AALDH1A1 | |
| SCHEMBL3904865 | 0.85 | HTR1A (0.51) | HTR1AKMT2A | |
| SCHEMBL26005943 | 0.83 | HTR1A (0.64) | HTR1ADRD2DRD4DRD3 | |
| SCHEMBL3906981 | 0.83 | MEN1 (0.57) | HTR1AKMT2AMEN1 | |
| SCHEMBL3911482 | 0.78 | CA12 (0.52) | HTR1AKMT2AMEN1ALDH1A1 | |
| SCHEMBL4546524 | 0.78 | HTR1A (0.48) | HPGDHTR1AKMT2ADRD2DRD4 | |
| SCHEMBL4546529 | 0.77 | HPGD (0.66) | HPGDHTR1AKMT2AMEN1ALDH1A1 | |
| SCHEMBL6981118 | 0.77 | HPGD (0.61) | HPGDHTR1AKMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131549-B1 | A METHOD FOR TREATING MOVEMENT DISORDERS WITH BEFIRADOL | PF MEDICAMENT (FR) | 2018-03-28 | — | — | EP | disclosed |
| EP-0946546-B1 | PYRIDIN-2-YL-METHYLAMINE DERIVATIVES, METHOD OF PREPARING AND APPLICATION AS MEDICINE | PF MEDICAMENT (FR) | 2003-06-25 | — | — | EP | disclosed |
| US-6020345-A | Pyridin-2-yl-methylamine derivatives, method of preparing and application as medicine | PIERRE FABRE MEDICAMENT (FR) | 2000-02-01 | — | — | US | disclosed |