⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1074458 | 1.00 | — | — | |
| SCHEMBL3699619 | 0.97 | — | — | |
| SCHEMBL38786 | 0.97 | — | — | |
| SCHEMBL38727 | 0.88 | — | — | |
| SCHEMBL3705302 | 0.88 | — | — | |
| SCHEMBL25327994 | 0.81 | KMT2A (0.36) | — | |
| SCHEMBL13858690 | 0.81 | KMT2A (0.36) | — | |
| SCHEMBL542776 | 0.81 | KMT2A (0.36) | — | |
| SCHEMBL11594630 | 0.81 | KMT2A (0.36) | — | |
| SCHEMBL7340365 | 0.81 | KMT2A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 489 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013802-B1 | N-CYCLOALKYL-N-[(BICYCLYLPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-14 | — | — | EP | claimed |
| US-9770022-B2 | N-cycloalkyl-N-[(bicyclylphenyl)methylene]-(thio)carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2017-09-26 | — | — | US | claimed |
| US-20160150777-A1 | N-CYCLOALKYL-N-[(BICYCLYLPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2016-06-02 | — | — | US | claimed |
| EP-3013802-A1 | N-CYCLOALKYL-N-[(BICYCLYLPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | Bayer Cropscience AG (DE) | 2016-05-04 | — | — | EP | claimed |
| WO-2014206953-A1 | N-CYCLOALKYL-N-[(BICYCLYLPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-12-31 | — | — | WO | claimed |
| WO-2014028669-A1 | NOVEL COMPOUNDS FOR MODULATION OF ROR-GAMMA ACTIVITY | BIOGEN IDEC MA INC. (US) | 2014-02-20 | — | — | WO | claimed |
| US-20120184556-A1 | SUBSTITUTED ENZOIMIDAZOLESULFONAMIDES AND SUBSTITUTED INDOLESULFONAMIDES AS MGLUR4 POTENTIATORS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2012-07-19 | — | — | US | claimed |
| EP-2456310-A1 | SUBSTITUTED BENZOIMIDAZOLESULFONAMIDES AND SUBSTITUTED INDOLESULFONAMIDES AS MGLUR4 POTENTIATORS | Vanderbilt University (US) | 2012-05-30 | — | — | EP | claimed |
| WO-2011011722-A1 | SUBSTITUTED BENZOIMIDAZOLESULFONAMIDES AND SUBSTITUTED INDOLESULFONAMIDES AS MGLUR4 POTENTIATORS | VANDERBILT UNIVERSITY (US) | 2011-01-27 | — | — | WO | claimed |
| US-20100130498-A1 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | DEUTSHES INSTITUT FUR ERNAHRUNGSFORSCHUNG POTSDAM- REHBRUCKE (DE) | 2010-05-27 | — | — | US | claimed |
| EP-2132564-A2 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke Stiftung des Öffentlichen Rechts (DE) | 2009-12-16 | — | — | EP | claimed |
| EP-1399431-B1 | NOVEL NITRILES USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2009-02-18 | — | — | EP | claimed |
| WO-2008135232-A1 | USE AND COMPOSITIONS OF PURINE DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CORTESE RICCARDO (IT) | 2008-11-13 | — | — | WO | claimed |
| WO-2008119527-A2 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POSTDAM-REHBRÜCKE STIFTUNG DES ÖFFENTLICHEN RECHTS (DE) | 2008-10-09 | — | — | WO | claimed |
| EP-1975611-A1 | Agonists of bitter taste receptors and uses thereof | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand (DE) | 2008-10-01 | — | — | EP | claimed |
| US-6982263-B2 | Nitriles useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-01-03 | — | — | US | claimed |
| US-20030119827-A1 | Novel nitriles useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-06-26 | — | — | US | claimed |
| US-5294531-A | BicycloUm.n.oealkane-1-ylcarbonylacetamide compound | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-15 | — | — | US | claimed |
| EP-3512852-B1 | TRAF 6 INHIBITORS | HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) | 2024-06-26 | — | — | EP | disclosed |
| EP-0574927-A1 | Silver halide color photographic light sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-12-22 | — | — | EP | disclosed |