Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982717 | 1.00 | F10 (0.41) | F10GAAHTTLMNARECQL | |
| SCHEMBL5972238 | 0.94 | F10 (0.42) | F10CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL6979748 | 0.78 | F10 (0.44) | F10GAAHTTLMNARECQL | |
| SCHEMBL6979752 | 0.78 | F10 (0.44) | F10GAAHTTLMNARECQL | |
| SCHEMBL24324199 | 0.77 | GAA (0.46) | F10GAAHTTLMNACHRM2 | |
| SCHEMBL14603121 | 0.74 | F10 (0.49) | F10CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL3276043 | 0.74 | F10 (0.46) | F10HTTCHRM2CHRM1CHRM3 | |
| SCHEMBL3276047 | 0.74 | F10 (0.46) | F10HTTCHRM2CHRM1CHRM3 | |
| SCHEMBL6985779 | 0.74 | F10 (0.49) | F10CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL7999305 | 0.74 | F10 (0.49) | F10CHRM2CHRM1CHRM3CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294716-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | Bristol-Myers Squibb Company (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096331-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |