Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 19/20 | 0.67 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 7/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218897 | 1.00 | ESR2 (0.67) | ESR2DEGS1ESR1CYP3A4CYP2C9 | |
| SCHEMBL698472 | 1.00 | ESR2 (0.67) | ESR2DEGS1ESR1CYP3A4CYP2C9 | |
| SCHEMBL28569320 | 1.00 | ESR2 (0.67) | ESR2DEGS1ESR1CYP3A4CYP2C9 | |
| SCHEMBL5581754 | 1.00 | ESR2 (0.67) | ESR2DEGS1ESR1CYP3A4CYP2C9 | |
| SCHEMBL28538819 | 1.00 | ESR2 (0.67) | ESR2DEGS1ESR1CYP3A4CYP2C9 | |
| SCHEMBL2095018 | 1.00 | ESR2 (0.67) | ESR2DEGS1ESR1CYP3A4CYP2C9 | |
| SCHEMBL28542248 | 1.00 | ESR2 (0.67) | ESR2DEGS1ESR1CYP3A4CYP2C9 | |
| SCHEMBL699003 | 1.00 | ESR2 (0.67) | ESR2DEGS1ESR1CYP3A4CYP2C9 | |
| Ammonia Solution, Strong SCHEMBL28956511 | 0.98 | ESR2 (0.64) | ESR2DEGS1ESR1CYP3A4CYP2C9 | |
| SCHEMBL56284 | 0.97 | ESR2 (0.69) | ESR2DEGS1ESR1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113412306-A | Polyarylate resin composition and molded article using the same | 尤尼吉可株式会社 | 2021-09-17 | — | — | CN | disclosed |
| CN-108699227-B | Polyarylate resin and resin composition thereof | 尤尼吉可株式会社 | 2021-05-14 | — | — | CN | disclosed |
| CN-108291014-B | Polyarylate resin, process for producing the same, and polyarylate resin composition | 尤尼吉可株式会社 | 2021-03-19 | — | — | CN | disclosed |
| WO-2020194996-A1 | RESIN COMPOSITION AND MOLDED OBJECT | 積水化学工業株式会社 | 2020-10-01 | — | — | WO | disclosed |
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20120052412-A1 | POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF | HONDA MOTOR CO., LTD. (JP) | 2012-03-01 | — | — | US | disclosed |
| EP-2424018-A1 | Polyarylene block copolymer having sulfonic acid group and use thereof | JSR Corporation (JP) | 2012-02-29 | — | — | EP | disclosed |
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| CN-1757130-A | Polymer electrolyte material, polymer electrolyte part, film electrode composite element and polymer electrolyte fuel cells | TORAY INDUSTRIES (JP) | 2006-04-05 | — | — | CN | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| CN-1099048-A | (being total to) polycarbonate compositions and preparation method thereof | DAICEL CHEM (JP) | 1995-02-22 | — | — | CN | disclosed |
| US-5292970-A | Alkylation | HUELS AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |
| EP-0122203-B1 | (HYDROCARBYLTHIO)PHENOLS AND THEIR PREPARATION | ETHYL CORPORATION (US) | 1986-12-30 | — | — | EP | disclosed |
| US-4533753-A | SULFIDING A PHENOL USING A DISULFIDE AND ALUMINUM PHENOXIDE CATALYST; OXIDATION RESISTANCE; OIL ADDITIVES | ETHYL CORPORATION (US) | 1985-08-06 | — | — | US | disclosed |
| WO-1984004092-A1 | (HYDROCARBYLTHIO)PHENOLS AND THEIR PREPARATION | ETHYL CORP (US) | 1984-10-25 | — | — | WO | disclosed |
| EP-0122203-A1 | (Hydrocarbylthio)phenols and their preparation | ETHYL CORPORATION (US) | 1984-10-17 | — | — | EP | disclosed |
| US-4351962-A | Process for the preparation of hydroxy benzene carboxaldehydes | RHONE POULENC INC. (US) | 1982-09-28 | — | — | US | disclosed |
| US-4255152-A | USING A DISPERSE DYE, WATER, AND AN ADDUCT OF ETHYLENE, PROPYLENE, OR STYRENE OXIDE AND A CYCLIC-SUBSTITUTED PHENOL; LEVELLING | CIBA-GEIGY CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | NR2C2, NR0B2, NR4A2 | ESR2 338/4885DEGS1 1723/4885ESR1 1871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.