Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983081 | 1.00 | CYP1A2 (0.56) | CYP1A2CYP2D6MAPTKMT2AALDH1A1 | |
| SCHEMBL9330267 | 0.91 | CYP1A2 (0.50) | CYP1A2CYP2D6MAPTKMT2AALDH1A1 | |
| SCHEMBL31406407 | 0.86 | ALDH1A1 (0.50) | CYP1A2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL16971052 | 0.86 | ALDH1A1 (0.50) | CYP1A2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL9756703 | 0.85 | CYP1A2 (0.53) | CYP1A2CYP2D6MAPTKMT2AALDH1A1 | |
| SCHEMBL9756705 | 0.85 | CYP1A2 (0.53) | CYP1A2CYP2D6MAPTKMT2AALDH1A1 | |
| SCHEMBL6809200 | 0.85 | CYP1A2 (0.53) | CYP1A2CYP2D6MAPTKMT2AALDH1A1 | |
| SCHEMBL6639628 | 0.85 | CYP1A2 (0.53) | CYP1A2CYP2D6MAPTKMT2AALDH1A1 | |
| SCHEMBL6981756 | 0.84 | TLR9 (0.53) | MAPTKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL9551020 | 0.84 | MAPT (0.49) | CYP1A2CYP2D6MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030078251-A1 | Benzoxazepinones and their use as squalene synthase inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1292585-A1 | BENZOXAZEPINONES AND THEIR USE AS SQUALENE SYNTHASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001098282-A1 | BENZOXAZEPINONES AND THEIR USE AS SQUALENE SYNTHASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 2001-12-27 | — | — | WO | disclosed |
| US-5237089-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1993-08-17 | — | — | US | disclosed |
| US-5062884-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1991-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078251-A1 | Benzoxazepinones and their use as squalene synthase inhibitors | SQLE, CYP17A1, ACOX1 | CYP1A2 380/4885CYP2D6 947/4885MAPT 4824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.