⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254501 | 1.00 | — | — | |
| SCHEMBL23356471 | 1.00 | — | — | |
| SCHEMBL108729 | 0.95 | ALDH1A1 (0.47) | — | |
| Hydrochloric Acid SCHEMBL9716582 | 0.95 | — | — | |
| Fluoride SCHEMBL8768209 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL9716581 | 0.91 | — | — | |
| SCHEMBL9351096 | 0.91 | ALDH1A1 (0.44) | — | |
| Chloropentafluoroethane SCHEMBL6153989 | 0.84 | ALDH1A1 (0.39) | — | |
| Perfluorocyclobutane SCHEMBL4855687 | 0.84 | ALDH1A1 (0.39) | — | |
| Norflurane SCHEMBL16178354 | 0.82 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759755-B1 | Thiadiazolylalkoxyphenyl derivatives, their preparation and their use anti-picornaviral agents | SANOFI SYNTHELABO (FR) | 2003-08-13 | — | — | EP | disclosed |
| US-5821257-A | Thiadiazoles and their uses as antipicornaviral agents | SANOFI (FR) | 1998-10-13 | — | — | US | disclosed |
| US-5750527-A | VIRICIDES | SANOFI (FR) | 1998-05-12 | — | — | US | disclosed |
| US-5650419-A | Thiadiazoles and their use as antipicornaviral agents | SANOFI, S.A. | 1997-07-22 | — | — | US | disclosed |
| US-5567719-A | Thiadiazoles and their use as antipicornaviral agents | STERLING WINTHROP, INC. (US) | 1996-10-22 | — | — | US | disclosed |
| US-5453433-A | Viricides; antiseptics to decontaminate polio, rhino and coxsackie viruses | STERLING WINTHROP INC. (US) | 1995-09-26 | — | — | US | disclosed |