Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27192566 | 0.85 | NPSR1 (0.50) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL7454968 | 0.83 | NPSR1 (0.51) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL27593353 | 0.80 | NPSR1 (0.43) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL2403566 | 0.78 | NPSR1 (0.53) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL2654349 | 0.76 | NPSR1 (0.51) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL8629996 | 0.76 | DAO (0.67) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL3333257 | 0.76 | NPSR1 (0.51) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL14448557 | 0.75 | NPSR1 (0.50) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL8254639 | 0.75 | NPSR1 (0.50) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL2406988 | 0.75 | NPSR1 (0.50) | NPSR1LMNAPPARGNCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110372692-A | Dihydroquinazoline ketone antiport process blocking agent, preparation method and the usage | 中国人民解放军军事科学院军事医学研究院 | 2019-10-25 | — | — | CN | disclosed |
| EP-1289980-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090100-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-11-29 | — | — | WO | disclosed |