Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.50 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454968 | 0.87 | NPSR1 (0.51) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL2403566 | 0.85 | NPSR1 (0.53) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL6983137 | 0.85 | NPSR1 (0.46) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL28012015 | 0.84 | CA12 (0.41) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL2654349 | 0.84 | NPSR1 (0.51) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL3333257 | 0.84 | NPSR1 (0.51) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL8254639 | 0.82 | NPSR1 (0.50) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL14448557 | 0.82 | NPSR1 (0.50) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| SCHEMBL2406988 | 0.82 | NPSR1 (0.50) | NPSR1LMNAPPARGNCOA1NCOA3 | |
| Hydrochloric Acid SCHEMBL2408434 | 0.81 | NPSR1 (0.49) | NPSR1LMNAPPARGNCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116910-A1 | Heterocycles as WIP1 Inhibitors | PMV PHARMACEUTICALS, INC. | 2024-04-11 | — | — | US | disclosed |
| CN-103687856-B | A novel 1,2,3,4-tetrahydroquinoline derivative useful for the treatment of diabetes | LILLY CO ELI | 2015-07-22 | — | — | CN | disclosed |
| CN-102648195-B | Novel spiropiperidine compounds | LILLY CO ELI | 2015-01-07 | — | — | CN | disclosed |
| CN-102648195-A | Novel spiropiperidine compounds | LILLY CO ELI | 2012-08-22 | — | — | CN | disclosed |
| CN-102131781-A | 1-(4-ureidobenzoyl)piperazine derivatives | ORGANON NV | 2011-07-20 | — | — | CN | disclosed |
| CN-1759095-A | N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARM INC (US) | 2006-04-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116910-A1 | Heterocycles as WIP1 Inhibitors | WAPL, WHR1, G3BP1 | NPSR1 4485/4885LMNA 4720/4885PPARG 2772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.