Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 10/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6981006 | 0.99 | CAMK2D (0.44) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| SCHEMBL6975973 | 0.90 | CAMK2D (0.53) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| SCHEMBL6977406 | 0.88 | CAMK2D (0.56) | CAMK2DPIM1CCNT1CDK9RPS6KB1 | |
| SCHEMBL6980479 | 0.84 | CAMK2D (0.45) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| SCHEMBL6973734 | 0.84 | CAMK2D (0.56) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| SCHEMBL7672205 | 0.84 | CAMK2D (0.48) | CAMK2DPIM1CCNT1CDK9RPS6KB1 | |
| Trifluoroacetic Acid SCHEMBL6982808 | 0.83 | CAMK2D (0.46) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| Hydrochloric Acid SCHEMBL6984367 | 0.83 | CAMK2D (0.55) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| SCHEMBL7676681 | 0.82 | CAMK2D (0.47) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| SCHEMBL6977746 | 0.81 | CAMK2D (0.51) | CAMK2DPIM1CCNT1CDK9CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095039-B1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-27 | — | — | EP | claimed |
| US-6346625-B1 | ENZYME INHIBITORS FOR PROTEIN KINASES | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | claimed |
| EP-1095039-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2001-05-02 | — | — | EP | claimed |
| WO-2000002877-A2 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-01-20 | — | — | WO | claimed |
| EP-1095039-B1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-27 | — | — | EP | disclosed |
| US-6346625-B1 | ENZYME INHIBITORS FOR PROTEIN KINASES | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | disclosed |