Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 7/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984625 | 0.88 | F10 (0.38) | F10 | |
| SCHEMBL6985644 | 0.85 | F10 (0.38) | KDM1AF10CHRM1 | |
| SCHEMBL6985286 | 0.81 | ACP1 (0.45) | ACP1KDM1A | |
| SCHEMBL6986433 | 0.81 | CHRM1 (0.38) | KDM1AF10CHRM1 | |
| SCHEMBL7092571 | 0.78 | F10 (0.42) | ACP1F10 | |
| SCHEMBL6987891 | 0.73 | F10 (0.38) | F10 | |
| SCHEMBL5868037 | 0.73 | AR (0.38) | F10CHRM1 | |
| SCHEMBL5868109 | 0.72 | KMT2A (0.41) | F10CHRM1 | |
| SCHEMBL5867988 | 0.70 | SLC6A4 (0.40) | F10CHRM1 | |
| SCHEMBL5868032 | 0.70 | F10 (0.38) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289954-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096303-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |