Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 9/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985644 | 0.88 | F10 (0.38) | CHRM1F10KDM1AHTR4MDM2 | |
| SCHEMBL6982644 | 0.88 | F10 (0.38) | F10CHRM2PLATKLKB1 | |
| SCHEMBL6983309 | 0.81 | ACP1 (0.42) | CHRM1F10KDM1A | |
| SCHEMBL7097521 | 0.76 | F10 (0.42) | CHRM1F10CHRM2CHRM4CHRM3 | |
| SCHEMBL5868109 | 0.76 | KMT2A (0.41) | CHRM1F10HTR4CHRM2CHRM4 | |
| SCHEMBL6987891 | 0.76 | F10 (0.38) | F10PLATKLKB1 | |
| SCHEMBL5867988 | 0.75 | SLC6A4 (0.40) | CHRM1F10HTR4PLATKLKB1 | |
| SCHEMBL6984625 | 0.70 | F10 (0.38) | F10PLATKLKB1 | |
| SCHEMBL5868037 | 0.69 | AR (0.38) | CHRM1F10PLATKLKB1 | |
| SCHEMBL6989921 | 0.69 | KMT2A (0.40) | CHRM1KDM1ACHRM2CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289954-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096303-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |