Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19889050 | 0.83 | HPGD (0.61) | HPGDKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL13645937 | 0.79 | HPGD (0.67) | HPGDKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL23564994 | 0.75 | HPGD (0.65) | HPGDKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL21392846 | 0.75 | HPGD (0.65) | HPGDKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5191019 | 0.74 | HPGD (0.63) | HPGDKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL28903374 | 0.72 | HPGD (0.58) | HPGDKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6646499 | 0.72 | KMT2A (0.57) | HPGDKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6646506 | 0.72 | KMT2A (0.57) | HPGDKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9577360 | 0.72 | PTGS1 (0.62) | HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL27046360 | 0.72 | HPGD (0.53) | HPGDKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322599-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2001096283-A9 | HIV INTEGRASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2002-10-17 | — | — | WO | disclosed |
| WO-2001096283-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |