Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805663 | 0.87 | PTGS1 (0.81) | PTGS1PTGS2KMT2AHPGDALDH1A1 | |
| SCHEMBL9220209 | 0.87 | PTGS1 (0.81) | PTGS1PTGS2KMT2AHPGDALDH1A1 | |
| SCHEMBL27598809 | 0.85 | PTGS1 (0.63) | PTGS1PTGS2KMT2AHPGDALDH1A1 | |
| SCHEMBL18252774 | 0.83 | PTGS1 (0.61) | PTGS1PTGS2KMT2AHPGDALDH1A1 | |
| SCHEMBL15695562 | 0.83 | PTGS1 (0.66) | PTGS1PTGS2KMT2AHPGDALDH1A1 | |
| SCHEMBL8796435 | 0.83 | PTGS1 (0.66) | PTGS1PTGS2KMT2AHPGDALDH1A1 | |
| SCHEMBL28574450 | 0.82 | PTGS1 (0.59) | PTGS1PTGS2KMT2AHPGDALDH1A1 | |
| SCHEMBL5717640 | 0.82 | PTGS2 (0.59) | PTGS1PTGS2KMT2AHPGDALDH1A1 | |
| SCHEMBL7402679 | 0.81 | PTGS1 (0.55) | PTGS1PTGS2KMT2AHPGDALDH1A1 | |
| SCHEMBL11452213 | 0.80 | PTGS1 (0.57) | PTGS1PTGS2ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |
| EP-0386243-A1 | PLATINUM (II) COMPLEXES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1990-09-12 | — | — | EP | disclosed |