Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694338 | 1.00 | KDM4E (0.54) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL1399177 | 1.00 | KDM4E (0.54) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL8535158 | 0.95 | KDM4E (0.48) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL9444635 | 0.93 | KDM4E (0.56) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL9444652 | 0.90 | LMNA (0.65) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL724112 | 0.90 | LMNA (0.65) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL5551085 | 0.90 | LMNA (0.65) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL29344590 | 0.90 | LMNA (0.65) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL6484167 | 0.85 | LMNA (0.40) | KDM4ELMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL8533676 | 0.85 | KDM4E (0.56) | KDM4ELMNAL3MBTL1TDP1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183255-B1 | BICYCLIC POLYAMINOACID METAL COMPLEXES, METHOD FOR PREPARING SAME AND USE IN MEDICAL IMAGING | GUERBET SA (FR) | 2003-03-05 | — | — | EP | disclosed |
| EP-0922700-B1 | Metal chelates of macrocyclic polyaminocarboxylic derivatives and their use for the diagnostic imaging | GUERBET SA (FR) | 2002-09-11 | — | — | EP | disclosed |
| US-6440956-B1 | Bicyclic polyaminoacid metal complexes, their process of preparation and their application in medical imaging | GUERBET (FR) | 2002-08-27 | — | — | US | disclosed |
| EP-1183255-A1 | BICYCLIC POLYAMINOACID METAL COMPLEXES, METHOD FOR PREPARING SAME AND USE IN MEDICAL IMAGING | GUERBET (FR) | 2002-03-06 | — | — | EP | disclosed |
| US-6187285-B1 | IN PARTICULAR MAGNETIC RESONANCE IMAGING (MRI) FOR MAGNETIC CATIONS. | GUERBET (FR) | 2001-02-13 | — | — | US | disclosed |
| WO-2000075141-A1 | BICYCLIC POLYAMINOACID METAL COMPLEXES, METHOD FOR PREPARING SAME AND USE IN MEDICAL IMAGING | GUERBET (FR) | 2000-12-14 | — | — | WO | disclosed |
| EP-0922700-A1 | Metal chelates of macrocyclic polyaminocarboxylic derivatives and their use for the diagnostic imaging | GUERBET (FR) | 1999-06-16 | — | — | EP | disclosed |