Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 5/20 | 0.41 |
| ▸ | DPP4 | P27487 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991960 | 0.90 | ANPEP (0.50) | ANPEPDPP4KMT2AALDH1A1LMNA | |
| SCHEMBL14500358 | 0.84 | ANPEP (0.49) | ANPEPDPP4KMT2AALDH1A1LMNA | |
| SCHEMBL1517978 | 0.82 | ANPEP (0.48) | ANPEPDPP4KMT2AALDH1A1LMNA | |
| SCHEMBL1517966 | 0.81 | ANPEP (0.47) | ANPEPDPP4KMT2AALDH1A1LMNA | |
| SCHEMBL12414747 | 0.81 | ANPEP (0.38) | ANPEPDPP4KMT2AALDH1A1LMNA | |
| SCHEMBL1517955 | 0.80 | ANPEP (0.46) | ANPEPDPP4KMT2AALDH1A1LMNA | |
| SCHEMBL12414748 | 0.79 | ANPEP (0.37) | ANPEPDPP4KMT2AALDH1A1LMNA | |
| SCHEMBL6986876 | 0.79 | MCL1 (0.39) | ANPEPDPP4KMT2AALDH1A1LMNA | |
| SCHEMBL13288152 | 0.76 | ANPEP (0.44) | ANPEPDPP4KMT2AALDH1A1LMNA | |
| SCHEMBL12414732 | 0.75 | ANPEP (0.39) | ANPEPDPP4NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507590-B2 | Fluorescent brighteners, methods of preparation thereof, fluorescent brightener compositions, and methods of preparation and uses thereof | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-08-13 | — | — | US | disclosed |
| US-20120203001-A1 | FLUORESCENT BRIGHTENERS, METHODS OF PREPARATION THEREOF, FLUORESCENT BRIGHTENER COMPOSITIONS, AND METHODS OF PREPARATION AND USES THEREOF | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2012-08-09 | — | — | US | disclosed |
| US-8183310-B2 | Fluorescent brighteners, methods of preparation thereof, fluorescent brightener compositions, and methods of preparation and uses thereof | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2012-05-22 | — | — | US | disclosed |
| US-20110065843-A1 | FLUORESCENT BRIGHTENERS, METHODS OF PREPARATION THEREOF, FLUORESCENT BRIGHTENER COMPOSITIONS, AND METHODS OF PREPARATION AND USES THEREOF | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065843-A1 | FLUORESCENT BRIGHTENERS, METHODS OF PREPARATION THEREOF, FLUORESCENT BRIGHTENER COMPOSITIONS, AND METHODS OF PREPARATION AND USES THEREOF | C1R, C1S, C9 | ANPEP 2771/4885DPP4 4467/4885KMT2A 3088/4885 |
| US-20120203001-A1 | FLUORESCENT BRIGHTENERS, METHODS OF PREPARATION THEREOF, FLUORESCENT BRIGHTENER COMPOSITIONS, AND METHODS OF PREPARATION AND USES THEREOF | C1R, C1S, C9 | ANPEP 2771/4885DPP4 4467/4885KMT2A 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.