Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 9/20 | 0.39 |
| ▸ | BCL2 | P10415 | 6/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.37 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 3/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1518018 | 0.91 | DPP4 (0.42) | MCL1BCL2BCL2L1DPP4NR1H2 | |
| SCHEMBL12414748 | 0.86 | ANPEP (0.37) | MCL1BCL2BCL2L1DPP4NR1H2 | |
| SCHEMBL14527523 | 0.85 | ALDH1A1 (0.41) | MCL1BCL2BCL2L1PRMT1ALDH1A1 | |
| SCHEMBL3287036 | 0.83 | MCL1 (0.53) | MCL1BCL2BCL2L1DPP4NR1H2 | |
| SCHEMBL3289495 | 0.81 | MCL1 (0.44) | MCL1BCL2BCL2L1DPP4NR1H2 | |
| SCHEMBL993935 | 0.80 | MCL1 (0.44) | MCL1BCL2BCL2L1DPP4NR1H2 | |
| SCHEMBL12414728 | 0.79 | MCL1 (0.33) | MCL1DPP4ANPEP | |
| SCHEMBL6984121 | 0.79 | ANPEP (0.41) | DPP4NR1H2NR1H3ANPEPPRMT1 | |
| SCHEMBL12414733 | 0.79 | ANPEP (0.38) | DPP4NR1H2NR1H3ANPEP | |
| SCHEMBL12414747 | 0.78 | ANPEP (0.38) | MCL1BCL2BCL2L1DPP4NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507590-B2 | Fluorescent brighteners, methods of preparation thereof, fluorescent brightener compositions, and methods of preparation and uses thereof | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-08-13 | — | — | US | disclosed |
| US-20120203001-A1 | FLUORESCENT BRIGHTENERS, METHODS OF PREPARATION THEREOF, FLUORESCENT BRIGHTENER COMPOSITIONS, AND METHODS OF PREPARATION AND USES THEREOF | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2012-08-09 | — | — | US | disclosed |
| US-8183310-B2 | Fluorescent brighteners, methods of preparation thereof, fluorescent brightener compositions, and methods of preparation and uses thereof | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2012-05-22 | — | — | US | disclosed |
| US-20110065843-A1 | FLUORESCENT BRIGHTENERS, METHODS OF PREPARATION THEREOF, FLUORESCENT BRIGHTENER COMPOSITIONS, AND METHODS OF PREPARATION AND USES THEREOF | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065843-A1 | FLUORESCENT BRIGHTENERS, METHODS OF PREPARATION THEREOF, FLUORESCENT BRIGHTENER COMPOSITIONS, AND METHODS OF PREPARATION AND USES THEREOF | C1R, C1S, C9 | MCL1 431/4885BCL2 2217/4885BCL2L1 2010/4885 |
| US-20120203001-A1 | FLUORESCENT BRIGHTENERS, METHODS OF PREPARATION THEREOF, FLUORESCENT BRIGHTENER COMPOSITIONS, AND METHODS OF PREPARATION AND USES THEREOF | C1R, C1S, C9 | MCL1 431/4885BCL2 2217/4885BCL2L1 2010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.