Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA4 | P22748 | 4/20 | 0.42 |
| ▸ | CA7 | P43166 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983588 | 0.91 | TP53 (0.54) | TP53ALDH1A1SMN1; SMN2LMNACXCR5 | |
| SCHEMBL6983194 | 0.91 | TP53 (0.47) | TP53ALDH1A1SMN1; SMN2LMNACXCR5 | |
| SCHEMBL6984940 | 0.87 | POLB (0.56) | TP53ALDH1A1SMN1; SMN2LMNACXCR5 | |
| SCHEMBL6986284 | 0.87 | TP53 (0.50) | TP53ALDH1A1SMN1; SMN2LMNACXCR5 | |
| SCHEMBL6981584 | 0.87 | POLB (0.52) | TP53ALDH1A1SMN1; SMN2LMNACXCR5 | |
| SCHEMBL6986065 | 0.86 | CA2 (0.55) | TP53ALDH1A1POLBHDAC1HDAC6 | |
| SCHEMBL6983551 | 0.86 | TP53 (0.47) | TP53ALDH1A1SMN1; SMN2LMNACXCR5 | |
| SCHEMBL6988260 | 0.86 | NPC1 (0.55) | TP53ALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL6978919 | 0.85 | MAPT (0.54) | TP53ALDH1A1SMN1; SMN2LMNACXCR5 | |
| SCHEMBL6985957 | 0.85 | FLT3 (0.53) | TP53ALDH1A1LMNAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596749-B2 | Neuropeptide y receptor ligand | LES LABORATOIRES SERVIER (FR) | 2003-07-22 | — | — | US | disclosed |
| EP-1044970-B1 | Aminotriazole compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-01-15 | — | — | EP | disclosed |
| US-20010018522-A1 | Aminotriazole compounds | LES LABORATOIRES SERVIER (FR) | 2001-08-30 | — | — | US | disclosed |
| US-6245916-B1 | USEFUL AS NEUROPEPTIDE Y RECEPTOR LIGANDS, ANXIOLYTIC AGENTS, SEDATIVES, AND VASOCONSTRICTORS | ADIR ET COMPAGNIE (FR) | 2001-06-12 | — | — | US | disclosed |
| EP-1044970-A1 | Aminotriazole compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010018522-A1 | Aminotriazole compounds | NPY1R, NPY2R, NPY4R | TP53 4077/4885ALDH1A1 2429/4885SMN1; SMN2 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.