Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24869869 | 0.86 | PIK3CD (0.31) | — | |
| SCHEMBL29821663 | 0.84 | — | — | |
| SCHEMBL5990357 | 0.84 | — | — | |
| SCHEMBL19608947 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TP53KDM4EGMNNLMNA | |
| SCHEMBL14238599 | 0.78 | PIK3CD (0.31) | — | |
| SCHEMBL5767343 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TP53KDM4EGMNNLMNA | |
| SCHEMBL13857000 | 0.74 | ALDH1A1 (0.37) | ALDH1A1TP53KDM4EGMNNLMNA | |
| SCHEMBL11972321 | 0.73 | — | — | |
| SCHEMBL1515499 | 0.73 | — | — | |
| SCHEMBL22459184 | 0.73 | GBA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0962457-B1 | Piperidones as tachykinin antagonists | PFIZER LTD (GB) | 2003-08-06 | — | — | EP | disclosed |
| EP-0962457-A1 | Piperidones as tachykinin antagonists | Pfizer Limited (GB) | 1999-12-08 | — | — | EP | disclosed |