SCHEMBL69845

SCHEMBL69845

O=C(Oc1ccccc1)c1ccc(C(=O)Oc2ccccc2)nc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.54
MAPT P10636 6/20 0.54
ALDH1A1 P00352 4/20 0.54
LMNA P02545 3/20 0.53
KDM4E B2RXH2 3/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
POLB P06746 1/20 0.51
KMT2A Q03164 4/20 0.50
MEN1 O00255 3/20 0.50
TDP1 Q9NUW8 1/20 0.50
TSHR P16473 1/20 0.49
PARP10 Q53GL7 1/20 0.49
NSD2 O96028 1/20 0.49
PRSS1 P07477 1/20 0.47
ACR P10323 1/20 0.47
TMPRSS15 P98073 1/20 0.47
P4HA1 P13674 1/20 0.47
MIF P14174 1/20 0.47
P4HTM Q9NXG6 1/20 0.47
NPC1 O15118 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68414 0.83 TDP1 (0.66) MAPTALDH1A1LMNAKDM4EPOLB
SCHEMBL9194472 0.83 MAPK1 (0.60) MAPK1MAPTALDH1A1LMNAKDM4E
SCHEMBL15373868 0.83 KMT2A (0.59) MAPK1MAPTALDH1A1LMNAKDM4E
SCHEMBL4813056 0.81 NAPRT (0.58) MAPTALDH1A1LMNAL3MBTL1POLB
SCHEMBL5826258 0.81 MAPT (0.59) MAPTALDH1A1LMNAKMT2AMEN1
SCHEMBL7233982 0.80 KMT2A (0.55) MAPK1MAPTALDH1A1LMNAKDM4E
SCHEMBL70034 0.79 PARP10 (0.70) MAPTALDH1A1LMNAL3MBTL1KMT2A
SCHEMBL28195517 0.79 KMT2A (0.47) MAPTALDH1A1KDM4EL3MBTL1POLB
SCHEMBL8824663 0.79 MAPT (0.63) MAPK1MAPTALDH1A1KDM4EKMT2A
6-Chloronicotinic Acid SCHEMBL6194163 0.78 NAPRT (0.67) MAPTALDH1A1LMNAL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 MAPK1 3382/4885MAPT 1923/4885ALDH1A1 1882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.