SCHEMBL68414

SCHEMBL68414

O=C(Oc1ccccc1)c1cnc(C(=O)Oc2ccccc2)cn1

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.66
KMT2A Q03164 3/20 0.66
MEN1 O00255 2/20 0.66
MAPT P10636 6/20 0.51
HSD17B10 Q99714 2/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
ALDH1A1 P00352 4/20 0.49
TSHR P16473 1/20 0.48
KDM4E B2RXH2 3/20 0.47
NSD2 O96028 1/20 0.47
POLB P06746 2/20 0.46
ALOX5 P09917 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
LMNA P02545 1/20 0.43
PARP10 Q53GL7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2217955 0.89 KMT2A (0.83) TDP1KMT2AMEN1MAPTALDH1A1
SCHEMBL5509020 0.83 TSHR (0.67) TDP1KMT2AMEN1MAPTHSD17B10
SCHEMBL29651934 0.83 TSHR (0.67) TDP1KMT2AMEN1MAPTHSD17B10
SCHEMBL69845 0.83 MAPK1 (0.54) TDP1KMT2AMEN1MAPTHSD17B10
SCHEMBL7233982 0.81 KMT2A (0.55) TDP1KMT2AMEN1MAPTALDH1A1
SCHEMBL17674189 0.81 ALDH1A1 (0.58) TDP1KMT2AMEN1MAPTHPGD
SCHEMBL30185288 0.80 MAPT (0.69) TDP1KMT2AMAPTHSD17B10HPGD
SCHEMBL3961211 0.80 MAPT (0.69) TDP1KMT2AMAPTHSD17B10HPGD
SCHEMBL28195517 0.79 KMT2A (0.47) TDP1KMT2AMEN1MAPTHSD17B10
SCHEMBL69458 0.79 MAPT (0.75) TDP1KMT2AMEN1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 TDP1 3534/4885KMT2A 1042/4885MEN1 4831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.