Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 15/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953038 | 1.00 | CCR1 (0.40) | CCR1TERTALDH1A1KCNH2PGK1 | |
| SCHEMBL12664449 | 0.83 | KCNH2 (0.45) | CCR1TERTALDH1A1KCNH2PGK1 | |
| SCHEMBL29805514 | 0.79 | CCR1 (0.40) | CCR1TERTALDH1A1PGK1PGK2 | |
| SCHEMBL29951735 | 0.79 | CCR1 (0.40) | CCR1TERTALDH1A1PGK1PGK2 | |
| SCHEMBL22354808 | 0.79 | CCR1 (0.40) | CCR1TERTALDH1A1PGK1PGK2 | |
| SCHEMBL945430 | 0.79 | CCR1 (0.40) | CCR1TERTALDH1A1PGK1PGK2 | |
| SCHEMBL9561000 | 0.79 | CCR1 (0.40) | CCR1TERTALDH1A1PGK1PGK2 | |
| SCHEMBL249047 | 0.79 | CCR1 (0.40) | CCR1TERTALDH1A1KCNH2 | |
| SCHEMBL11818083 | 0.77 | KCNH2 (0.66) | CCR1ALDH1A1KCNH2 | |
| SCHEMBL3299995 | 0.77 | KCNH2 (0.50) | KCNH2PGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9174960-B2 | Compounds useful against kinetoplastideae parasites | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-11-03 | — | — | US | disclosed |
| EP-0946546-B1 | PYRIDIN-2-YL-METHYLAMINE DERIVATIVES, METHOD OF PREPARING AND APPLICATION AS MEDICINE | PF MEDICAMENT (FR) | 2003-06-25 | — | — | EP | disclosed |
| US-6020345-A | Pyridin-2-yl-methylamine derivatives, method of preparing and application as medicine | PIERRE FABRE MEDICAMENT (FR) | 2000-02-01 | — | — | US | disclosed |
| EP-0946546-A1 | PYRIDIN-2-YL-METHYLAMINE DERIVATIVES, METHOD OF PREPARING AND APPLICATION AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998022459-A1 | PYRIDIN-2-YL-METHYLAMINE DERIVATIVES, METHOD OF PREPARING AND APPLICATION AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 1998-05-28 | — | — | WO | disclosed |