SCHEMBL945430

SCHEMBL945430

O=Cc1cccc(CO)n1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.40
TERT O14746 13/20 0.39
F2R P25116 1/20 0.38
PGK1 P00558 1/20 0.36
PGK2 P07205 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29805514 1.00 CCR1 (0.40) CCR1TERTF2RPGK1PGK2
SCHEMBL9868200 0.86 SMN1; SMN2 (0.41) CCR1TERTALDH1A1
SCHEMBL12664449 0.83 KCNH2 (0.45) CCR1TERTPGK1PGK2ALDH1A1
SCHEMBL29953038 0.79 CCR1 (0.40) CCR1TERTPGK1PGK2ALDH1A1
SCHEMBL22354808 0.79 CCR1 (0.40) CCR1TERTPGK1PGK2ALDH1A1
SCHEMBL249047 0.79 CCR1 (0.40) CCR1TERTF2RALDH1A1
SCHEMBL29951735 0.79 CCR1 (0.40) CCR1TERTPGK1PGK2ALDH1A1
SCHEMBL6984612 0.79 CCR1 (0.40) CCR1TERTPGK1PGK2ALDH1A1
SCHEMBL9561000 0.79 CCR1 (0.40) CCR1TERTPGK1PGK2ALDH1A1
SCHEMBL2928608 0.79 CCR1 (0.40) CCR1F2RPGK1PGK2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250101475-A1 MONOOXYGENASE MUTANTS FOR BIOSYNTHESIS OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE AND A METHOD FOR PREPARATION OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE USING THE SAID MONOOXYGENASE MUTANTS VIO CHEMICALS AG (CH) 2025-03-27 US disclosed
US-11945838-B2 Method for synthesis of protein amphiphiles INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IN) 2024-04-02 US disclosed
CN-115057836-B Ester compound and preparation method and application thereof 浙江糖能科技有限公司 2023-11-28 CN disclosed
CN-114656431-B Alpha, beta-unsaturated ketone compound, and preparation method and application thereof 浙江糖能科技有限公司 2023-11-28 CN disclosed
US-20230250456-A1 METHOD FOR PREPARATION OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE VIA ENZYMATIC CATALYSIS VIO CHEMICALS AG (CH) 2023-08-10 US disclosed
US-20230250456-A1 METHOD FOR PREPARATION OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE VIA ENZYMATIC CATALYSIS VIO CHEMICALS AG (CH) 2023-08-10 US disclosed
WO-2023126510-A1 MONOOXYGENASE MUTANTS FOR BIOSYNTHESIS OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE AND A METHOD FOR PREPARATION OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE USING THE SAID MONOOXYGENASE MUTANTS VIO CHEMICALS AG (CH) 2023-07-06 WO disclosed
WO-2023126510-A1 MONOOXYGENASE MUTANTS FOR BIOSYNTHESIS OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE AND A METHOD FOR PREPARATION OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE USING THE SAID MONOOXYGENASE MUTANTS VIO CHEMICALS AG (CH) 2023-07-06 WO disclosed
US-11685741-B2 Fluorescent probes UNIVERSITY OF MASSACHUSETTS (US) 2023-06-27 US disclosed
US-11685741-B2 Fluorescent probes UNIVERSITY OF MASSACHUSETTS (US) 2023-06-27 US disclosed
US-6703373-B1 ANTICARCINOGENIC AGENTS BANYU PHARMACEUTICAL CO., LTD. (JP) 2004-03-09 US disclosed
US-20020049190-A1 Pharmaceutical compositions comprising metal complexes ANORMED INC. (CA) 2002-04-25 US disclosed
EP-1163247-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING METAL COMPLEXES ANORMED INC. (CA) 2001-12-19 EP disclosed
WO-2000056743-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING METAL COMPLEXES ANORMED INC. (CA) 2000-09-28 WO disclosed
EP-0763033-A1 IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-03-19 EP disclosed
WO-1995032198-A1 IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-11-30 WO disclosed
EP-0533695-B1 IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY PFIZER (US) 1994-10-05 EP disclosed
US-5322847-A Inhibit platelet activating factor, block leukotriene D4 receptors PFIZER INC. (US) 1994-06-21 US disclosed
EP-0533695-A1 IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY. PFIZER (US) 1993-03-31 EP disclosed
WO-1991017163-A1 IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY PFIZER INC. (US) 1991-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250456-A1 METHOD FOR PREPARATION OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE VIA ENZYMATIC CATALYSIS DCXR, LOX, XDH CCR1 2292/4885TERT 2863/4885F2R 817/4885
US-11685741-B2 Fluorescent probes FECH, CHERP, SLC40A1 CCR1 4362/4885TERT 3951/4885F2R 4184/4885
US-20020049190-A1 Pharmaceutical compositions comprising metal complexes CFD, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, F12 CCR1 378/4885TERT 3143/4885F2R 1118/4885
US-11945838-B2 Method for synthesis of protein amphiphiles PTMS, VAC14, PDIA6 CCR1 3640/4885TERT 3130/4885F2R 4713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.