Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.87 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734720 | 1.00 | ACHE (0.87) | ACHEEPHX1EPHX2TDP1 | |
| SCHEMBL10724300 | 1.00 | ACHE (0.87) | ACHEEPHX1EPHX2TDP1 | |
| SCHEMBL13700681 | 0.98 | ACHE (0.90) | ACHEEPHX1EPHX2TDP1 | |
| SCHEMBL8801572 | 0.98 | ACHE (0.83) | ACHEEPHX1EPHX2TDP1 | |
| SCHEMBL27051138 | 0.95 | ACHE (0.90) | ACHEEPHX1EPHX2 | |
| SCHEMBL14891267 | 0.95 | ACHE (0.90) | ACHEEPHX1EPHX2 | |
| SCHEMBL27051136 | 0.95 | ACHE (0.90) | ACHEEPHX1EPHX2 | |
| SCHEMBL10897404 | 0.93 | ACHE (0.81) | ACHEEPHX1EPHX2 | |
| SCHEMBL9693989 | 0.93 | ACHE (0.81) | ACHEEPHX1EPHX2 | |
| SCHEMBL5245046 | 0.93 | ACHE (1.00) | ACHEEPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090100-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-11-29 | — | — | WO | disclosed |