Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.66 |
| ▸ | NOS3 | P29474 | 2/20 | 0.65 |
| ▸ | NOS2 | P35228 | 2/20 | 0.65 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984671 | 1.00 | NOS1 (0.66) | NOS1NOS3NOS2QRFPR | |
| SCHEMBL4396067 | 0.83 | NOS1 (0.68) | NOS1NOS3NOS2QRFPR | |
| Iodide SCHEMBL4402647 | 0.81 | NOS1 (0.66) | NOS1NOS3NOS2QRFPR | |
| SCHEMBL6280369 | 0.80 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL6966996 | 0.79 | NOS1 (1.00) | NOS1NOS3NOS2QRFPR | |
| Iodide SCHEMBL9053048 | 0.78 | NOS1 (0.96) | NOS1NOS3NOS2 | |
| SCHEMBL9038075 | 0.77 | NOS1 (0.80) | NOS1NOS3NOS2QRFPR | |
| Bromide SCHEMBL6966297 | 0.76 | NOS1 (0.80) | NOS1NOS3NOS2QRFPR | |
| Hydrochloric Acid SCHEMBL9220217 | 0.76 | NOS1 (0.78) | NOS1NOS3NOS2QRFPR | |
| SCHEMBL4400343 | 0.75 | NOS1 (0.56) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318149-A1 | Amidine derivatives, their preparation and application as medicines and pharmaceutical compositions containing them | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2003-06-11 | — | — | EP | claimed |