Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8192980 | 0.95 | RAB9A (0.48) | RAB9AHTTGAACACNA1GSMN1; SMN2 | |
| SCHEMBL8192977 | 0.95 | RAB9A (0.48) | RAB9AHTTGAACACNA1GSMN1; SMN2 | |
| SCHEMBL8191640 | 0.94 | RAB9A (0.47) | RAB9AHTTGAACACNA1GSMN1; SMN2 | |
| SCHEMBL17976301 | 0.90 | HTT (0.48) | RAB9AHTTGAACACNA1GSMN1; SMN2 | |
| SCHEMBL17976298 | 0.90 | HTT (0.48) | RAB9AHTTGAACACNA1GSMN1; SMN2 | |
| SCHEMBL6984507 | 0.90 | HTT (0.50) | RAB9AHTTGAASMN1; SMN2LMNA | |
| SCHEMBL8192954 | 0.90 | RAB9A (0.44) | RAB9AHTTGAACACNA1GSMN1; SMN2 | |
| SCHEMBL8192956 | 0.90 | RAB9A (0.44) | RAB9AHTTGAACACNA1GSMN1; SMN2 | |
| SCHEMBL8177450 | 0.89 | RET (0.45) | RAB9AHTTGAAHPGDALDH1A1 | |
| SCHEMBL8190763 | 0.89 | RAB9A (0.48) | RAB9AHTTGAACACNA1GSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071665-B1 | SUBSTITUTED INDOLINONES HAVING AN INHIBITING EFFECT ON KINASES AND CYCLINE/CDK COMPLEXES | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-10-01 | — | — | EP | disclosed |
| US-6169106-B1 | ANTITUMOUR AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-01-02 | — | — | US | disclosed |