Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984701 | 1.00 | AKR1C3 (0.49) | AKR1C3MAOAMAOBTACR2ENPP2 | |
| SCHEMBL7255418 | 0.91 | FDPS (0.47) | AKR1C3ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7258826 | 0.91 | FDPS (0.47) | AKR1C3ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL5220608 | 0.89 | TACR2 (0.52) | MAOAMAOBTACR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5218024 | 0.89 | AKR1C3 (0.56) | AKR1C3MAOAMAOBTACR2ENPP2 | |
| SCHEMBL5220602 | 0.89 | TACR2 (0.52) | MAOAMAOBTACR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5213944 | 0.83 | TACR2 (0.54) | AKR1C3MAOAMAOBTACR2ALDH1A1 | |
| SCHEMBL9077155 | 0.83 | TACR2 (0.54) | AKR1C3MAOAMAOBTACR2ALDH1A1 | |
| SCHEMBL29721221 | 0.83 | TACR2 (0.54) | AKR1C3MAOAMAOBTACR2ALDH1A1 | |
| SCHEMBL7259952 | 0.81 | CYP2C9 (0.44) | AKR1C3MAOAMAOBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313471-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | Oxford GlycoSciences (UK) Limited (GB) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002017915-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | OXFORD GLYCOSCIENCES (UK) LIMITED (GB) | 2002-03-07 | — | — | WO | disclosed |