⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11954073 | 0.50 | — | — | |
| SCHEMBL14158450 | 0.50 | — | — | |
| SCHEMBL320324 | 0.50 | — | — | |
| SCHEMBL515670 | 0.45 | — | — | |
| SCHEMBL18649660 | 0.45 | — | — | |
| SCHEMBL248228 | 0.44 | — | — | |
| SCHEMBL108867 | 0.35 | — | — | |
| SCHEMBL63148 | 0.35 | — | — | |
| SCHEMBL320609 | 0.35 | MEN1 (1.00) | — | |
| SCHEMBL3387 | 0.35 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103237801-B | Quinoline or quinazoline derivatives having apoptosis-inducing activity on cells | HANMI HOLDINGS Co.,Ltd. (KR) | 2015-11-25 | — | — | CN | claimed |
| CN-103237801-A | Quinoline or quinazoline derivatives having apoptosis-inducing activity on cells | HANMI HOLDINGS CO LTD | 2013-08-07 | — | — | CN | claimed |
| EP-4408843-A1 | NOVEL SUBSTITUTED SULFONYLUREA COMPOUNDS AS INHIBITORS OF INTERLEUKIN-1 ACTIVITY | Viva Star Biosciences (Suzhou) Co., Ltd. (CN) | 2024-08-07 | — | — | EP | disclosed |
| US-20240246908-A1 | TEAD INHIBITORS | ORION CORPORATION (FI) | 2024-07-25 | — | — | US | disclosed |
| WO-2024125626-A1 | NITROGENOUS COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | NUPHASE THERAPEUTICS (HANGZHOU) LIMITED., CO. (CN) | 2024-06-20 | — | — | WO | disclosed |
| EP-4384510-A1 | COMPOUNDS TARGETING MUTANT OF P53 | Jacobio Pharmaceuticals Co., Ltd. (CN) | 2024-06-19 | — | — | EP | disclosed |
| CN-111825701-B | Tricyclic FXR modulator compounds containing benzothiazole | 正大天晴药业集团股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| EP-4217348-A1 | INDOLINE COMPOUNDS AND DERIVATIVES AS EGFR INHIBITORS | BeiGene, Ltd. (KY) | 2023-08-02 | — | — | EP | disclosed |
| WO-2023125530-A1 | ANTIBODY DRUG CONJUGATES | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |
| WO-2023056264-A1 | NOVEL SUBSTITUTED SULFONYLUREA COMPOUNDS AS INHIBITORS OF INTERLEUKIN-1 ACTIVITY | VIVA STAR BIOSCIENCES (SUZHOU) CO., LTD. (CN) | 2023-04-06 | — | — | WO | disclosed |
| CN-112585128-B | Pyrazole derivatives as MALT1 inhibitors | 詹森药业有限公司 | 2023-02-21 | — | — | CN | disclosed |
| CN-103122001-A | Polo-like kinase inhibitors | TAKEDA PHARMACEUTICAL | 2013-05-29 | — | — | CN | disclosed |
| WO-2012158099-A1 | A PROCESS FOR THE PREPARATION OF BENZYL [(3AS,4R,6S,6AR)-6-HYDROXY-2,2- DIMETHYLTETRAHYDRO-3AH-CYCLOPENTA[D][1,3]DIOXOL]-4-YL]CARBAMATE AND INTERMEDIATES IN THE PROCESS | ASTRAZENECA AB (SE) | 2012-11-22 | — | — | WO | disclosed |
| CN-102149716-A | Process for the preparation of [1S-[1α,2α,3β (1S*, 2R*), 5β]]-3-[7-[2-(3, 4-difluorophenyl)-cyclopropylamino]-5-(propylthio)-3H-1,2, 3-triazolo [4,5-d] pyrimidin-3-yl]-5-(2-hydroxyethoxy) cyclopentane-1, 2-diol and intermediates thereof | ASTRAZENECA AB | 2011-08-10 | — | — | CN | disclosed |
| CN-101917995-A | POLO-like kinase inhibitors | TAKEDA PHARMACEUTICAL | 2010-12-15 | — | — | CN | disclosed |
| CN-101687864-A | 1-cyanocyclopropyl-derivatives as cathepsin K inhibitors | ASTRAZENECA AB | 2010-03-31 | — | — | CN | disclosed |
| CN-101374818-A | Pyrimidine derivatives | ASTRAZENECA AB (SE) | 2009-02-25 | — | — | CN | disclosed |
| CN-1478088-A | Benzothiophene derivatives, process for their preparation and their use | ά��ʵ��������˾ | 2004-02-25 | — | — | CN | disclosed |
| EP-1337528-A2 | BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF | LABORATORIOS VITA, S.A. (ES) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002044170-A2 | BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF | LABORATORIOS VITA, S.A. (ES) | 2002-06-06 | — | — | WO | disclosed |