Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28012315 | 0.92 | ALDH1A1 (0.55) | ALDH1A1F2HPGDMMP1MMP2 | |
| SCHEMBL5457 | 0.92 | — | — | |
| SCHEMBL2778162 | 0.92 | ALDH1A1 (0.55) | ALDH1A1F2HPGDMMP1MMP2 | |
| SCHEMBL14511334 | 0.92 | ALDH1A1 (0.55) | ALDH1A1F2HPGDMMP1MMP2 | |
| SCHEMBL7749269 | 0.92 | ALDH1A1 (0.55) | ALDH1A1F2HPGDMMP1MMP2 | |
| SCHEMBL23963672 | 0.92 | ALDH1A1 (0.55) | ALDH1A1F2HPGDMMP1MMP2 | |
| SCHEMBL4129583 | 0.92 | ALDH1A1 (0.55) | ALDH1A1F2HPGDMMP1MMP2 | |
| SCHEMBL8364865 | 0.92 | ALDH1A1 (0.55) | ALDH1A1F2HPGDMMP1MMP2 | |
| SCHEMBL1363949 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL7413294 | 0.89 | ALDH1A1 (0.52) | ALDH1A1F2HPGDMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320529-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002024684-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-03-28 | — | — | WO | disclosed |