⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14167163 | 0.98 | TSHR (0.52) | — | |
| SCHEMBL22757319 | 0.92 | TSHR (0.46) | — | |
| SCHEMBL8566167 | 0.92 | TSHR (0.46) | — | |
| SCHEMBL1188266 | 0.92 | TSHR (0.46) | — | |
| SCHEMBL697966 | 0.91 | TSHR (0.50) | — | |
| SCHEMBL697221 | 0.91 | ALDH1A1 (0.50) | — | |
| SCHEMBL6883317 | 0.90 | TSHR (0.44) | — | |
| SCHEMBL7605599 | 0.90 | TSHR (0.44) | — | |
| SCHEMBL338018 | 0.90 | TSHR (0.44) | — | |
| SCHEMBL6883320 | 0.90 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438203-B | Preparation method of 2-cyclopropylpropionaldehyde | 淮安国瑞化工有限公司 | 2020-08-21 | — | — | CN | claimed |
| WO-2025224262-A1 | COMBINATION THERAPIES COMPRISING A CDK2 DEGRADER AND A CDK4/6 INHIBITOR | MONTE ROSA THERAPEUTICS AG (CH) | 2025-10-30 | — | — | WO | disclosed |
| EP-4608816-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | Monte Rosa Therapeutics AG (CH) | 2025-09-03 | — | — | EP | disclosed |
| US-20250263395-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS AG (CH) | 2025-08-21 | — | — | US | disclosed |
| CN-118724796-A | Phenylpropionic acid derivative, and preparation method and application thereof | 广东众生睿创生物科技有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-118619932-A | GPR40 agonist and preparation method and application thereof | 广东众生睿创生物科技有限公司 | 2024-09-10 | — | — | CN | disclosed |
| WO-2024092039-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |
| CN-116472273-A | Antidiabetic compounds and compositions | 宁康瑞珠生物制药(珠海)有限公司 | 2023-07-21 | — | — | CN | disclosed |
| WO-2023134712-A1 | ANTIDIABETIC COMPOUNDS AND COMPOSITIONS | REZUBIO PHARMACEUTICALS CO., LTD (CN) | 2023-07-20 | — | — | WO | disclosed |
| CN-109438203-B | Preparation method of 2-cyclopropylpropionaldehyde | 淮安国瑞化工有限公司 | 2020-08-21 | — | — | CN | disclosed |
| US-20090143590-A1 | Process for the Preparation of Montelukast and its Salts | MATRIX LABORATORIES LTD. (IN) | 2009-06-04 | — | — | US | disclosed |
| US-20080275243-A1 | Process for the Preparation of Polymorphs, Solvates of Aripiprazole Using Aripiprazole Acid Salts | SATYANARAYANA CHAVA | 2008-11-06 | — | — | US | disclosed |
| EP-1981853-A1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | Pfizer Limited (GB) | 2008-10-22 | — | — | EP | disclosed |
| US-20080125473-A1 | SUBSTITUTED IMIDAZOLES | PFIZER LIMITED (GB) | 2008-05-29 | — | — | US | disclosed |
| US-20080119536-A1 | SUBSTITUTED IMIDAZOLES | PFIZER LIMITED (GB) | 2008-05-22 | — | — | US | disclosed |
| WO-2007083207-A1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LIMITED (GB) | 2007-07-26 | — | — | WO | disclosed |
| US-20070167506-A1 | SUBSTITUTED IMIDAZOLES | PFIZER INC. (US) | 2007-07-19 | — | — | US | disclosed |
| CN-1890249-A | Substituted 3-amino-thieno[2,3-b] pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | BOEHRINGER INGELHEIM PHARMA (US) | 2007-01-03 | — | — | CN | disclosed |
| EP-0050534-B1 | ESTERS OF CYCLOPROPANE-CARBOXYLIC ACIDS RELATED TO PYRETHRIC ACID, THEIR PREPARATION AND USE AS INSECTICIDES | ROUSSEL-UCLAF (FR) | 1985-04-03 | — | — | EP | disclosed |
| EP-0050534-A1 | Esters of cyclopropane-carboxylic acids related to pyrethric acid, their preparation and use as insecticides | ROUSSEL-UCLAF (FR) | 1982-04-28 | — | — | EP | disclosed |