SCHEMBL6984962

SCHEMBL6984962

COc1ccc2c(c1)c1c(n2Cc2ccccc2)CCCC1C(=O)NCCC(N)=O

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.61
PLA2G2A P14555 15/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11824216 0.91 HTR6 (0.61) HTR6PLA2G2A
SCHEMBL11834372 0.89 HTR6 (0.64) HTR6PLA2G2A
SCHEMBL11826210 0.89 HTR6 (0.64) HTR6PLA2G2A
SCHEMBL6699386 0.88 HTR6 (0.67) HTR6PLA2G2A
SCHEMBL11826084 0.87 HTR6 (0.66) HTR6PLA2G2A
SCHEMBL6699402 0.87 HTR6 (0.71) HTR6PLA2G2A
SCHEMBL11824093 0.85 HTR6 (0.70) HTR6PLA2G2A
SCHEMBL11827008 0.84 HTR6 (0.69) HTR6PLA2G2A
Hydrochloric Acid SCHEMBL11827022 0.84 HTR6 (0.69) HTR6PLA2G2A
SCHEMBL5764974 0.82 HTR6 (0.72) HTR6PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0839806-B1 Substituted tricyclics LILLY CO ELI (US) 2003-07-09 EP disclosed
EP-0839806-A1 Substituted tricyclics ELI LILLY AND COMPANY (US) 1998-05-06 EP disclosed