Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 18/20 | 0.47 |
| ▸ | FPR1 | P21462 | 15/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987862 | 0.90 | F10 (0.54) | F10FPR2FPR1 | |
| SCHEMBL6988832 | 0.88 | FPR2 (0.49) | F10FPR2FPR1 | |
| SCHEMBL6981073 | 0.88 | F10 (0.56) | F10FPR2FPR1 | |
| SCHEMBL7090057 | 0.86 | F10 (0.46) | F10FPR2FPR1ALDH1A1 | |
| SCHEMBL6985267 | 0.86 | FPR2 (0.55) | F10FPR2FPR1 | |
| SCHEMBL6988559 | 0.82 | FPR2 (0.50) | F10FPR2FPR1 | |
| SCHEMBL4683741 | 0.81 | F10 (0.74) | F10FPR2FPR1 | |
| SCHEMBL7139450 | 0.81 | FPR2 (0.55) | F10FPR2FPR1 | |
| SCHEMBL28381115 | 0.80 | F10 (0.48) | F10FPR2FPR1 | |
| SCHEMBL28382471 | 0.80 | FPR2 (0.67) | FPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337251-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2003-08-27 | — | — | EP | claimed |
| WO-2002102380-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-12-27 | — | — | WO | claimed |