Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384052 | 0.85 | MAPT (0.55) | MAPTKDM4EGAACA12CA1 | |
| SCHEMBL30529634 | 0.85 | MAPT (0.55) | MAPTKDM4EGAACA12CA1 | |
| Hydrochloric Acid SCHEMBL27745533 | 0.84 | MAPT (0.54) | MAPTKDM4EGAACA12CA1 | |
| SCHEMBL10909390 | 0.82 | KDM4E (0.50) | MAPTKDM4EGAACA12CA1 | |
| SCHEMBL27510896 | 0.82 | KDM4E (0.51) | MAPTKDM4EGAACA12CA1 | |
| SCHEMBL665048 | 0.80 | CA12 (0.53) | MAPTKDM4EGAACA12CA1 | |
| Hydrochloric Acid SCHEMBL8021718 | 0.79 | KDM4E (0.53) | MAPTKDM4EGAACA12CA1 | |
| SCHEMBL7336195 | 0.79 | PPARG (0.53) | MAPTKDM4EPPARGPPARDPPARA | |
| SCHEMBL6890994 | 0.79 | POLB (0.54) | MAPTKDM4EPPARGPPARDPPARA | |
| SCHEMBL1495030 | 0.78 | MAPT (0.50) | MAPTKDM4EGAACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |