SCHEMBL665048

SCHEMBL665048

COc1ccc2c(c1)CCCN2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
HRH3 Q9Y5N1 2/20 0.52
KDM4E B2RXH2 2/20 0.50
MAPT P10636 2/20 0.50
GAA P10253 2/20 0.50
ALDH1A1 P00352 2/20 0.50
LMNA P02545 1/20 0.50
TP53 P04637 1/20 0.50
THRB P10828 1/20 0.50
ALOX15 P16050 1/20 0.50
CASP1 P29466 1/20 0.50
HTT P42858 1/20 0.50
CASP7 P55210 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
PDE3B Q13370 1/20 0.49
PDE3A Q14432 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8021718 0.98 KDM4E (0.53) CA12CA1CA2CA9HRH3
SCHEMBL2778234 0.95 HRH3 (0.48) CA12CA1CA2CA9HRH3
Hydrochloric Acid SCHEMBL3526192 0.93 KDM4E (0.48) CA12CA1CA2CA9HRH3
SCHEMBL565913 0.89 DRD2 (0.53) HRH3ALDH1A1PDE3BPDE3ABCL2
Hydrochloric Acid SCHEMBL2208192 0.87 DRD2 (0.52) HRH3ALDH1A1PDE3BPDE3ABCL2
Hydrochloric Acid SCHEMBL2208190 0.87 DRD2 (0.52) HRH3ALDH1A1PDE3BPDE3ABCL2
SCHEMBL28951119 0.87 KDM4E (0.46) CA12CA1CA2CA9HRH3
SCHEMBL1395133 0.86 HRH3 (0.52) HRH3PDE3BPDE3AKDRPARP1
SCHEMBL30471897 0.86 HRH3 (0.52) HRH3PDE3BPDE3AKDRPARP1
SCHEMBL12079229 0.81 PDE3B (0.53) HRH3ALDH1A1LMNATHRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 102785 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119931978-A Application of monoamine oxidase as catalyst in preparation of quinoline nitrogen heterocyclic compound 河北工业大学 2025-05-06 CN claimed
CN-117229275-B Novel 2-acetamido thiazole compound and preparation method and application thereof 北京中医药大学 2024-06-18 CN claimed
CN-115626889-B Organic chemical conversion method for oxidative dehydrogenation of nitrogen-containing heterocyclic compound 南京工业大学 2024-04-30 CN claimed
WO-2023165502-A1 BACTERIAL PREPARATION EXPRESSING VEGFR3 D2 POLYPEPTIDE, METHOD FOR CONSTRUCTING SAME AND USE THEREOF 中国科学院动物研究所 2023-09-07 WO claimed
WO-2023125831-A1 METHOD FOR COLLECTING MICROBIAL BODIES FROM FERMENTATION SOLUTION SUITABLE FOR AUTOMATIC OPERATION 无锡药明生物技术股份有限公司 2023-07-06 WO claimed
CN-116376858-A Application of monoamine oxidase from microorganism as catalyst in preparation of quinoline or quinoline derivative 浙江大学杭州国际科创中心 2023-07-04 CN claimed
WO-2023115677-A1 SYSTEM FOR PRODUCING INDUSTRIAL PROTEINS USING CARBON-CONTAINING INDUSTRIAL GASES 北京首钢朗泽科技股份有限公司 2023-06-29 WO claimed
WO-2023109383-A1 WHOOPING COUGH ANTIGEN RECOMBINANT EXPRESSION VECTOR, AND ENGINEERED BACTERIUM THEREOF AND USE THEREOF 远大赛威信生命科学(南京)有限公司 2023-06-22 WO claimed
WO-2023088181-A1 COMPOSITION, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 上海昌进生物科技有限公司 2023-05-25 WO claimed
WO-2023041062-A1 PSEUDOMONAS AND USE THEREOF 中国石油化工股份有限公司 2023-03-23 WO claimed
CN-87102201-A The purification method of room air and device thereof 1988-10-12 CN claimed
CN-85104232-B Anaerobic fermentation equipment using bioenergy stirring device 司尚锁 1988-07-13 CN claimed
CN-87106754-A Method for separating and purifying amylase, adsorbent used in method, and separation and purification apparatus 1988-05-04 CN claimed
CN-86106611-A The new method and new technology that baker's active dried yeast is produced 1988-04-13 CN claimed
CN-86101724-B Method for preparing delicious meat food from Mucor 北京市营养源研究所 1987-12-09 CN claimed
CN-85108135-A The edible fungus products are cultured by solid and liquid culture media comprehensively. Method for preparing strain, fungus beverage, mycelium, and protein food 1987-05-06 CN claimed
CN-86106687-A In fermentation process, remove the method for defoamer 1987-03-18 CN claimed
CN-85101908-A What nematode stored and transported improves one's methods 1987-01-10 CN claimed
CN-85104057-A The purification of vinasse and utilization 1986-11-19 CN claimed
US-4087561-A Control of nitrosamine formation in nitride cured meat with 1,2,3,4-tetrahydro-quinoline compounds CANADA PACKERS LIMITED (CA) 1978-05-02 US claimed