Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.48 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29818168 | 0.81 | PDGFRB (0.62) | PDGFRBPDGFRACYP2A6BIRC5CA12 | |
| SCHEMBL2772360 | 0.80 | PDGFRB (0.77) | POLBPDGFRBPDGFRACYP2A6BIRC5 | |
| SCHEMBL32667946 | 0.80 | PDGFRB (0.77) | POLBPDGFRBPDGFRACYP2A6BIRC5 | |
| SCHEMBL17944740 | 0.80 | PDGFRB (0.61) | PDGFRBPDGFRACYP2A6BIRC5CA12 | |
| SCHEMBL24412080 | 0.79 | PDGFRB (0.65) | POLBPDGFRBPDGFRACYP2A6BIRC5 | |
| SCHEMBL10498512 | 0.79 | PDGFRB (0.54) | PDGFRBPDGFRACYP2A6BIRC5CA12 | |
| SCHEMBL10051400 | 0.79 | PDGFRB (0.54) | POLBPDGFRBPDGFRACYP2A6BIRC5 | |
| SCHEMBL10051316 | 0.77 | PDGFRB (0.57) | PDGFRBPDGFRACYP2A6BIRC5CA12 | |
| SCHEMBL19943005 | 0.76 | PDGFRB (0.66) | PDGFRBPDGFRACYP2A6BIRC5CA12 | |
| SCHEMBL12580362 | 0.76 | PDGFRB (0.66) | PDGFRBPDGFRACYP2A6BIRC5CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150362-A | ADMINISTERING 1,3,5-SUBSTITUTED TRIAZINE COMPOUNDS TO THE PATIENT SUFFERING FROM ANGIOGENIC DISEASES | ABBVIE INC. | 2000-11-21 | — | — | US | claimed |
| EP-1037886-B1 | TRIAZINE ANGIOGENESIS INHIBITORS | ABBOTT LAB (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6288228-B1 | DIAMINOTRIAZINE DERIVATIVES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |
| US-6150362-A | ADMINISTERING 1,3,5-SUBSTITUTED TRIAZINE COMPOUNDS TO THE PATIENT SUFFERING FROM ANGIOGENIC DISEASES | ABBVIE INC. | 2000-11-21 | — | — | US | disclosed |