Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | SDCBP | O00560 | 1/20 | 0.30 |
| ▸ | SDC2 | P34741 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984360 | 0.79 | — | — | |
| SCHEMBL8318662 | 0.79 | DPP8 (0.36) | KDM4ERECQL | |
| SCHEMBL6490844 | 0.77 | KDM4E (0.35) | KDM4ERECQLSYKMAPTRAB9A | |
| SCHEMBL6492438 | 0.76 | BRD4 (0.38) | KDM4ERECQL | |
| SCHEMBL2603740 | 0.76 | KDM4E (0.47) | KDM4ERECQL | |
| SCHEMBL4460457 | 0.66 | CHKA (0.38) | RAB9A | |
| SCHEMBL8489586 | 0.63 | CA12 (0.43) | KDM4ERECQL | |
| SCHEMBL8315757 | 0.63 | CA12 (0.36) | KDM4ERECQL | |
| SCHEMBL2255811 | 0.62 | NAMPT (0.43) | NAMPT | |
| SCHEMBL28641279 | 0.61 | HRH3 (0.44) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131321-B1 | INDOLE DERIVATIVES AND THEIR USE AS SEROTONIN RECEPTOR LIGANDS | LILLY CO ELI (GB) | 2003-09-10 | — | — | EP | disclosed |
| US-6329366-B1 | HETEROCYCLIC, PIPERIDINE, INDOLE DERIVITIVES FOR TREATMENT OF NERVOUS SYSTEM DISORDERS AND SEROTONIN ANTAGONIST | ELI LILLY AND COMPANY LIMITED (GB) | 2001-12-11 | — | — | US | disclosed |