⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985370 | 0.79 | NAMPT (0.32) | — | |
| SCHEMBL6490844 | 0.75 | KDM4E (0.35) | — | |
| SCHEMBL8318662 | 0.72 | DPP8 (0.36) | — | |
| SCHEMBL8317800 | 0.70 | RYR2 (0.42) | — | |
| SCHEMBL6492438 | 0.70 | BRD4 (0.38) | — | |
| SCHEMBL2603740 | 0.70 | KDM4E (0.47) | — | |
| SCHEMBL6984270 | 0.68 | ALDH1A1 (0.42) | — | |
| SCHEMBL8316408 | 0.65 | DPP8 (0.36) | — | |
| SCHEMBL8315757 | 0.58 | CA12 (0.36) | — | |
| SCHEMBL8317166 | 0.57 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286992-A1 | PIPERIDYINDOLES AS SEROTONIN RECEPTOR LIGANDS | ELI LILLY AND COMPANY (US) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001087881-A1 | PIPERIDYINDOLES AS SEROTONIN RECEPTOR LIGANDS | ELI LILLY AND COMPANY (US) | 2001-11-22 | — | — | WO | disclosed |