Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 9/20 | 0.48 |
| ▸ | FNTB | P49356 | 9/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088695 | 0.92 | FNTA (0.50) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6975071 | 0.91 | FNTA (0.49) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6982939 | 0.91 | FNTA (0.49) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL7087365 | 0.91 | FNTA (0.52) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL7087481 | 0.88 | FNTA (0.49) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6982184 | 0.88 | FNTA (0.51) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL7081052 | 0.86 | FNTA (0.46) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6979471 | 0.84 | FNTA (0.46) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL7084214 | 0.83 | FNTA (0.56) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL7087345 | 0.82 | FNTA (0.64) | FNTAFNTBPGGT1BCYP3A4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045846-B1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2003-05-02 | — | — | EP | disclosed |
| US-6472526-B1 | SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE OR PHARMACEUTICALLY ACCEPTABLE SALTS OR ISOMERS THEREOF, IN PHARMACEUTICAL COMPOSITION AND INTERMEDIATES | LG CHEMICAL LTD. (KR) | 2002-10-29 | — | — | US | disclosed |