Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 3/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KDM6B | O15054 | 2/20 | 0.47 |
| ▸ | KDM5C | P41229 | 2/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.47 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.47 |
| ▸ | TET3 | O43151 | 1/20 | 0.47 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | ASPH | Q12797 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.47 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.47 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985789 | 0.93 | HDAC1 (0.51) | KDM4AKDM4CHDAC1HDAC6ALDH1A1 | |
| SCHEMBL6235628 | 0.81 | KDM4C (0.48) | KDM4AKDM4CHDAC1HDAC6ALKBH5 | |
| SCHEMBL5210601 | 0.80 | KDM4E (0.56) | KDM4AKDM4CHDAC1HDAC6ALKBH5 | |
| SCHEMBL28967781 | 0.78 | CYP2C9 (0.54) | KDM4AKDM4CALKBH5FTOALDH1A1 | |
| SCHEMBL19615585 | 0.78 | ALDH1A1 (0.50) | KDM4AKDM4CALKBH5FTOALDH1A1 | |
| SCHEMBL30253543 | 0.78 | CYP2C9 (0.54) | KDM4AKDM4CALKBH5FTOALDH1A1 | |
| SCHEMBL28967801 | 0.77 | CYP2C9 (0.53) | KDM4AKDM4CALKBH5FTOALDH1A1 | |
| Hydrochloric Acid SCHEMBL30253848 | 0.77 | CYP2C9 (0.53) | KDM4AKDM4CALKBH5FTOALDH1A1 | |
| SCHEMBL30253736 | 0.77 | CYP2C9 (0.53) | KDM4AKDM4CALKBH5FTOALDH1A1 | |
| Hydrochloric Acid SCHEMBL28967775 | 0.77 | CYP2C9 (0.53) | KDM4AKDM4CALKBH5FTOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |