Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
| ▸ | DRD3 | P35462 | 5/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986028 | 1.00 | F10 (0.51) | F10PRSS1DRD2DRD3FAAH | |
| SCHEMBL6986023 | 1.00 | F10 (0.51) | F10PRSS1DRD2DRD3FAAH | |
| SCHEMBL6980593 | 0.94 | F10 (0.51) | F10PRSS1DRD2DRD3FAAH | |
| SCHEMBL6980596 | 0.94 | F10 (0.51) | F10PRSS1DRD2DRD3FAAH | |
| SCHEMBL6980591 | 0.94 | F10 (0.51) | F10PRSS1DRD2DRD3FAAH | |
| SCHEMBL6979303 | 0.91 | F10 (0.49) | F10PRSS1DRD2DRD3FAAH | |
| SCHEMBL6979297 | 0.91 | F10 (0.49) | F10PRSS1DRD2DRD3FAAH | |
| SCHEMBL6979292 | 0.91 | F10 (0.49) | F10PRSS1DRD2DRD3FAAH | |
| SCHEMBL12536885 | 0.88 | RORC (0.52) | F10PRSS1DRD2DRD3FAAH | |
| SCHEMBL5110560 | 0.85 | RORC (0.57) | F10PRSS1RORCSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934265-B1 | AMIDINOPHENYL-PYRROLIDINES, -PYRROLINES, AND -ISOXAZOLIDINES AND DERIVATIVES THEREOF | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6057342-A | INHIBITORS OF TRYPSIN-LIKE SERINE PROTEASE ENZYMES, ESPECIALLY FACTOR XA, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME AS ANTICOAGULANT AGENTS FOR TREATMENT AND PREVENTION OF THROMBOEMBOLIC DISORDERS | DUPONT PHARMACEUTICAL CO. (US) | 2000-05-02 | — | — | US | disclosed |