Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10986437 | 0.88 | NQO1 (0.48) | NQO1KDM4ETSHRKMT2AALDH1A1 | |
| SCHEMBL10986380 | 0.88 | CA12 (0.47) | NQO1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL16955556 | 0.83 | NQO1 (0.43) | NQO1KDM4ETSHRTDP1MEN1 | |
| SCHEMBL6799758 | 0.83 | NQO1 (0.52) | NQO1KDM4ETSHRTDP1MEN1 | |
| SCHEMBL16962794 | 0.82 | KMT2A (0.43) | NQO1KDM4ETSHRTDP1MEN1 | |
| SCHEMBL16953615 | 0.82 | S1PR1 (0.43) | NQO1MAPT | |
| SCHEMBL16951200 | 0.82 | L3MBTL1 (0.43) | NQO1KDM4ETSHRTDP1MEN1 | |
| SCHEMBL29657372 | 0.80 | NQO1 (0.59) | NQO1KDM4ETSHRTDP1MEN1 | |
| SCHEMBL2498271 | 0.80 | NQO1 (0.59) | NQO1KDM4ETSHRTDP1MEN1 | |
| SCHEMBL16951722 | 0.79 | MAPT (0.47) | KDM4ETSHRTDP1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349027-B | A kind of preparation method of high-order column aromatic hydrocarbons | 浙江大学 | 2019-03-26 | — | — | CN | claimed |
| CN-106349027-A | Preparation method of high-order column aromatic hydrocarbon | 浙江大学 | 2017-01-25 | — | — | CN | claimed |
| CN-106349027-B | A kind of preparation method of high-order column aromatic hydrocarbons | 浙江大学 | 2019-03-26 | — | — | CN | disclosed |
| CN-106349027-A | Preparation method of high-order column aromatic hydrocarbon | 浙江大学 | 2017-01-25 | — | — | CN | disclosed |
| EP-0985671-B1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-0638075-B1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| CN-1309561-A | Therapeutic agent for erectile dysfunction | MOCHIDA PHARM CO LTD (JP) | 2001-08-22 | — | — | CN | disclosed |
| US-6197768-B1 | THERAPY, PREVENTION ISCHEMIC HEART DISEASE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| CN-1284075-A | Novel compounds having CGMP-PDE inhibitory effect | MOCHIDA PHARM CO LTD (JP) | 2001-02-14 | — | — | CN | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |
| EP-0437186-B1 | Melamine derivatives as stabilizers for chlorine containing polymers | CIBA GEIGY AG (CH) | 1995-12-06 | — | — | EP | disclosed |
| EP-0638075-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| WO-1994019335-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |
| EP-0365483-B1 | Mercaptobenzoic-acid esters used as stabilizers for chlorine-containing polymers | CIBA GEIGY AG (CH) | 1993-12-29 | — | — | EP | disclosed |
| US-5272192-A | Melamine derivatives as stabilizers for chloride-containing polymers | CIBA-GEIGY CORPORATION (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0437186-A1 | Melamine derivatives as stabilizers for chlorine containing polymers | CIBA-GEIGY AG (CH) | 1991-07-17 | — | — | EP | disclosed |
| US-5030671-A | Metal carboxylate and/or phenolate mixture | CIBA-GEIGY CORPORATION (US) | 1991-07-09 | — | — | US | disclosed |
| EP-0365483-A1 | Mercaptobenzoic-acid esters used as stabilizers for chlorine-containing polymers | CIBA-GEIGY AG (CH) | 1990-04-25 | — | — | EP | disclosed |
| US-4497815-A | 1-(N-Substituted carbamoyl)-5-fluorouracil derivatives and the carcinostatic agents containing same as active ingredients | Ozaki, Shoichiro (JP) | 1985-02-05 | — | — | US | disclosed |