Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.37 |
| ▸ | F2 | P00734 | 6/20 | 0.37 |
| ▸ | MBTPS1 | Q14703 | 4/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985983 | 0.82 | F10 (0.43) | F10F2MBTPS1 | |
| SCHEMBL6985986 | 0.72 | MBTPS1 (0.44) | F10F2MBTPS1 | |
| SCHEMBL7140946 | 0.65 | SLC6A2 (0.40) | F10F2 | |
| SCHEMBL6598734 | 0.62 | F10 (0.36) | F10F2PLGPRSS1PRSS2 | |
| SCHEMBL6599020 | 0.62 | F10 (0.36) | F10F2PLGPRSS1PRSS2 | |
| SCHEMBL3133910 | 0.61 | PARP10 (0.64) | F10F2 | |
| SCHEMBL13766409 | 0.61 | HRH1 (0.54) | F10F2 | |
| SCHEMBL6290015 | 0.61 | HRH1 (0.54) | F10F2 | |
| SCHEMBL12735781 | 0.61 | HRH1 (0.55) | F10F2 | |
| SCHEMBL14578145 | 0.60 | HRH1 (0.71) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246619-A4 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| EP-1246619-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001045700-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-06-28 | — | — | WO | disclosed |