Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTPS1 | Q14703 | 6/20 | 0.44 |
| ▸ | F10 | P00742 | 7/20 | 0.43 |
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985983 | 0.81 | F10 (0.43) | MBTPS1F10F2SLC6A2SLC6A4 | |
| SCHEMBL6979203 | 0.80 | SLC6A2 (0.43) | F10F2SLC6A2SLC6A4KCNH2 | |
| SCHEMBL7143857 | 0.76 | SLC6A2 (0.43) | SLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL6980416 | 0.76 | SLC6A2 (0.43) | MBTPS1SLC6A2SLC6A4KCNH2SLC6A3 | |
| SCHEMBL6598738 | 0.76 | F10 (0.38) | F10F2SLC6A2SLC6A4KCNH2 | |
| SCHEMBL6599638 | 0.73 | F10 (0.39) | F10F2SLC6A2SLC6A4 | |
| SCHEMBL6986072 | 0.72 | F10 (0.37) | MBTPS1F10F2 | |
| SCHEMBL6600076 | 0.71 | F10 (0.36) | F10F2SLC6A2SLC6A4 | |
| SCHEMBL6601397 | 0.70 | F10 (0.34) | MBTPS1F10F2SLC6A2SLC6A4 | |
| SCHEMBL6981912 | 0.69 | REN (0.44) | SLC6A2SLC6A4KCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246619-A4 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| EP-1246619-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001045700-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-06-28 | — | — | WO | disclosed |