Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 7/20 | 0.33 |
| ▸ | CNR2 | P34972 | 7/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MGMT | P16455 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984398 | 0.88 | ALDH1A1 (0.42) | SLC6A4SLC6A2SLC6A3HTR1ACNR1 | |
| SCHEMBL6982103 | 0.88 | CHRM1 (0.38) | SLC6A4CHRM1HTR2C | |
| Hydrochloric Acid SCHEMBL6987919 | 0.87 | ALDH1A1 (0.41) | SLC6A4SLC6A2SLC6A3HTR1ACNR1 | |
| Hydrochloric Acid SCHEMBL6987410 | 0.87 | CHRM1 (0.37) | SLC6A4CHRM1HTR2C | |
| SCHEMBL6989372 | 0.80 | CHRM1 (0.38) | SLC6A4CHRM1MPOHTR2CALDH1A1 | |
| SCHEMBL6985817 | 0.77 | CHRM1 (0.35) | CHRM1 | |
| SCHEMBL6988257 | 0.76 | CHRM1 (0.59) | CHRM1 | |
| SCHEMBL6981312 | 0.76 | CHRM1 (0.43) | CHRM1 | |
| SCHEMBL6980919 | 0.76 | CHRM1 (0.48) | CHRM1 | |
| SCHEMBL6989733 | 0.75 | CHRM1 (0.33) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189902-B1 | 7-OXO-2-AZABICYCLO[2.2.1]HEPTANES AS SELECTIVE MUSCARINIC RECEPTOR ANTAGONIST | LILLY CO ELI (US) | 2003-08-27 | — | — | EP | claimed |