Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29299422 | 0.83 | TSHR (0.58) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL11566607 | 0.82 | TSHR (0.57) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL679046 | 0.82 | TSHR (0.61) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL27323340 | 0.82 | TSHR (0.61) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL30781045 | 0.82 | TSHR (0.61) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL356063 | 0.79 | TSHR (1.00) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL9710728 | 0.79 | TSHR (1.00) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL27471576 | 0.79 | TSHR (0.57) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL10918542 | 0.79 | TSHR (0.71) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL18970231 | 0.78 | TSHR (0.56) | TSHRLMNAALDH1A1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113773235-B | Synthesis method of clorsulon | 北大方正集团有限公司 | 2022-06-17 | — | — | CN | claimed |
| CN-113773235-A | Synthesis method of clorsulon | 北大方正集团有限公司 | 2021-12-10 | — | — | CN | claimed |
| EP-1294695-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-03-26 | — | — | EP | claimed |
| WO-2001085694-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-11-15 | — | — | WO | claimed |
| CN-113773235-B | Synthesis method of clorsulon | 北大方正集团有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-113773235-A | Synthesis method of clorsulon | 北大方正集团有限公司 | 2021-12-10 | — | — | CN | disclosed |
| EP-1294695-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001085694-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-11-15 | — | — | WO | disclosed |