Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 2/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.65 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.64 |
| ▸ | SIRT3 | Q9NTG7 | 13/20 | 0.62 |
| ▸ | KDM5A | P29375 | 1/20 | 0.62 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.62 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593771 | 0.88 | NR1H4 (0.55) | EYA3PTPN1NR1H4 | |
| SCHEMBL15121511 | 0.86 | ESR1 (0.51) | EYA3PTPN1NR1H4 | |
| SCHEMBL6140267 | 0.85 | SIRT3 (0.49) | EYA3PTPN1NR1H4SIRT3 | |
| SCHEMBL6140406 | 0.84 | ESR1 (0.51) | — | |
| SCHEMBL25389194 | 0.83 | KDM5A (0.84) | EYA3PTPN1NR1H4SIRT3KDM5A | |
| SCHEMBL29736895 | 0.83 | EYA3 (0.76) | EYA3PTPN1NR1H4SIRT3KDM5A | |
| SCHEMBL9591605 | 0.83 | EYA3 (0.76) | EYA3PTPN1NR1H4SIRT3KDM5A | |
| SCHEMBL25389924 | 0.83 | EYA3 (0.82) | EYA3PTPN1NR1H4SIRT3KDM5A | |
| SCHEMBL15121439 | 0.83 | ESR1 (0.48) | NR1H4 | |
| SCHEMBL15121438 | 0.83 | ESR1 (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315708-A1 | AMINOALKENYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002016338-A1 | AMINOALKENYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-02-28 | — | — | WO | disclosed |