Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.50 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17198969 | 0.86 | CNR1 (0.54) | ST14CNR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15940162 | 0.84 | ESRRG (0.57) | ST14ESRRGCNR1EPHX1HIF1A | |
| SCHEMBL6679010 | 0.83 | ST14 (0.50) | ST14ESRRGHIF1ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8079626 | 0.81 | ST14 (0.49) | ST14ESRRGHIF1ANPC1RAB9A | |
| SCHEMBL625333 | 0.79 | ESRRG (0.55) | ST14ESRRGHIF1ANPC1RAB9A | |
| SCHEMBL15939579 | 0.78 | EPHX1 (0.69) | ST14ESRRGCNR1EPHX1NPC1 | |
| SCHEMBL26709576 | 0.77 | ESRRG (0.57) | ST14ESRRGHIF1ANPC1RAB9A | |
| SCHEMBL160035 | 0.77 | ESRRG (0.54) | ESRRGCNR1EPHX1HIF1ANPC1 | |
| SCHEMBL915701 | 0.75 | ESRRG (0.55) | ST14ESRRGEPHX1HIF1ANPC1 | |
| SCHEMBL6415914 | 0.75 | ST14 (0.54) | ST14ESRRGHIF1APPIDGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1332127-A2 | AMIDINO-UREA SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SNYTHESIS | Warner-Lambert Company LLC (US) | 2003-08-06 | — | — | EP | disclosed |
| WO-2002036554-A2 | AMIDINO-UREA SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SNYTHESIS | WARNER-LAMBERT COMPANY LLC (US) | 2002-05-10 | — | — | WO | disclosed |