Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPID | Q08752 | 2/20 | 0.47 |
| ▸ | PPIB | P23284 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | PPIG | Q13427 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15940162 | 0.91 | ESRRG (0.57) | ESRRGEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27799797 | 0.84 | KDM4E (0.66) | ESRRGEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15939579 | 0.84 | EPHX1 (0.69) | ESRRGEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27800119 | 0.83 | HPGD (0.64) | NPC1RAB9ASMN1; SMN2CNR1HPGD | |
| SCHEMBL27821072 | 0.83 | CNR1 (0.66) | EPHX1NPC1RAB9ASMN1; SMN2CNR1 | |
| SCHEMBL157397 | 0.83 | CNR1 (0.57) | EPHX1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL160344 | 0.82 | EPHX1 (0.71) | EPHX1NPC1RAB9ASMN1; SMN2CNR1 | |
| SCHEMBL15652114 | 0.82 | PPID (0.65) | EPHX1NPC1SMN1; SMN2PPIDPPIB | |
| SCHEMBL25003647 | 0.81 | SMN1; SMN2 (0.59) | ESRRGEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19334528 | 0.81 | ACACB (0.56) | ESRRGPPIDHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10752624-B2 | Kinase inhibitors | ORIGENIS GMBH (DE) | 2020-08-25 | — | — | US | disclosed |
| US-20180305356-A1 | NOVEL KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2018-10-25 | — | — | US | disclosed |
| US-10000482-B2 | Kinase inhibitors | ORIGENIS GMBH (DE) | 2018-06-19 | — | — | US | disclosed |
| US-9918473-B2 | Use of aryl carbamates in agriculture and other plant-related areas | North Carolian State University (US) | 2018-03-20 | — | — | US | disclosed |
| US-9918473-B2 | Use of aryl carbamates in agriculture and other plant-related areas | North Carolian State University (US) | 2018-03-20 | — | — | US | disclosed |
| US-9918473-B2 | Use of aryl carbamates in agriculture and other plant-related areas | North Carolian State University (US) | 2018-03-20 | — | — | US | disclosed |
| US-9637491-B2 | Pyrazolo[4,3-D]pyrimidines as kinase inhibitors | ORIGENIS GMBH (DE) | 2017-05-02 | — | — | US | disclosed |
| US-20160353739-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | UNIV NORTH CAROLINA STATE (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160353739-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | UNIV NORTH CAROLINA STATE (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160353739-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | UNIV NORTH CAROLINA STATE (US) | 2016-12-08 | — | — | US | disclosed |
| US-20130172187-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | NORTH CAROLINA STATE UNIVERSITY | 2013-07-04 | — | — | US | disclosed |
| US-20130172187-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | NORTH CAROLINA STATE UNIVERSITY | 2013-07-04 | — | — | US | disclosed |
| US-20130172187-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | NORTH CAROLINA STATE UNIVERSITY | 2013-07-04 | — | — | US | disclosed |
| US-20130123225-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | NORTH CAROLINA STATE UNIVERSITY | 2013-05-16 | — | — | US | disclosed |
| US-20130123225-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | NORTH CAROLINA STATE UNIVERSITY | 2013-05-16 | — | — | US | disclosed |
| US-20130123225-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | NORTH CAROLINA STATE UNIVERSITY | 2013-05-16 | — | — | US | disclosed |
| WO-2012030986-A2 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012030986-A2 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012006276-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-12 | — | — | WO | disclosed |
| WO-2012006276-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172187-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | CTRC, ACE, DDT | ESRRG 2453/4885EPHX1 3677/4885NPC1 2027/4885 |
| US-20160353739-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | CTRC, ACE, DDT | ESRRG 2453/4885EPHX1 3677/4885NPC1 2027/4885 |
| US-20130123225-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | PGLS, BLVRB, AADAC | ESRRG 2209/4885EPHX1 2418/4885NPC1 3790/4885 |
| US-20180305356-A1 | NOVEL KINASE INHIBITORS | LRRK2, MYLK2, MYLK | ESRRG 1199/4885EPHX1 4062/4885NPC1 4398/4885 |
| US-10000482-B2 | Kinase inhibitors | LRRK2, MYLK2, MYLK | ESRRG 1374/4885EPHX1 4150/4885NPC1 4434/4885 |
| US-10752624-B2 | Kinase inhibitors | LRRK2, MYLK2, MYLK | ESRRG 1374/4885EPHX1 4150/4885NPC1 4434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.